Results 21 to 30 of about 228,598 (287)

Information encoding and reconstruction from the phase of action potentials

Frontiers in Systems Neuroscience, 2009
Fundamental questions in neural coding are how neurons encode, transfer, and reconstruct information from the pattern of action potentials exchanged between different brain structures.
Zoltan Nadasdy
doaj   +1 more source

Depolarization of the conductance-voltage relationship in the NaV1.5 mutant, E1784K, is due to altered fast inactivation.

PLoS ONE, 2017
E1784K is the most common mixed long QT syndrome/Brugada syndrome mutant in the cardiac voltage-gated sodium channel NaV1.5. E1784K shifts the midpoint of the channel conductance-voltage relationship to more depolarized membrane potentials and ...
Colin H Peters, Alec Yu, Wandi Zhu, Jonathan R Silva, Peter C Ruben   +4 more
doaj   +1 more source

Oxidation-reduction and photophysical properties of isomeric forms of Safranin.

PLoS ONE, 2022
Safranine O is widely used in the bioenergetics community as an indicator dye to determine membrane potentials and as an electron transfer mediator in potentiometric titrations.
Eskil M E Andersen, Hsin Wang, Joshua S H Khoo, Jose F Cerda, Ronald L Koder   +4 more
doaj   +1 more source

Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling

Nature Communications, 2016
‘Analogue’ modulation by somatic membrane potentials can modify ‘digital’ axonal action potentials. Here, the authors show that analogue modulation can occur in back-propagating dendritic action potentials and calcium signals, leading to signal ...
János Brunner, János Szabadics
doaj   +1 more source

Membrane Activity of Melittin and Magainin-I at Low Peptide-to-Lipid Ratio: Different Types of Pores and Translocation Mechanisms

Biomolecules
Antimicrobial peptides (AMPs) are believed to be a prominent alternative to the common antibiotics. However, despite decades of research, there are still no good clinical examples of peptide-based antimicrobial drugs for system application.
Marta V. Volovik, Oleg V. Batishchev
doaj   +1 more source

Descending Vasa Recta Endothelial Membrane Potential Response Requires Pericyte Communication. [PDF]

PLoS ONE, 2016
Using dual-cell electrophysiological recording, we examined the routes for equilibration of membrane potential between the pericytes and endothelia that comprise the descending vasa recta (DVR) wall.
Zhong Zhang, Kristie Payne, Thomas L Pallone   +2 more
doaj   +1 more source

Involvement of MAPKs and PLC Pathways in Modulation of Pacemaking Activity by So-Cheong-Ryong-Tang in Interstitial Cells of Cajal from Murine Small Intestine

The Scientific World Journal, 2013
Purpose. Interstitial cells of Cajal (ICCs) are the pacemaker cells that generate slow waves in the gastrointestinal (GI) tract. We have aimed to investigate the effects of Socheongryong-Tang (SCRT) in ICCs from mouse’s small intestine. Methods.
Min Woo Hwang, Hee Jung Lee, Ho Joon Song, Byung Joo Kim   +3 more
doaj   +1 more source

Selective Anticancer Activity and Safety Profile of Chlorochalcones: Impact on Breast Cancer, Blood, and Endothelial Cells

Cells
In the pursuit of novel anticancer therapies, assessing their selectivity and safety profile towards healthy cells is crucial. This study investigated chlorochalcones, derivatives of 2′-hydroxychalcone containing a chlorine atom, for their impact on ...
Sylwia Cyboran-Mikołajczyk, Karolina Matczak, Teresa Kaźmierczak, Natalia Trochanowska-Pauk, Tomasz Walski, Raghvendra Bohara, Karol Bukowski, Agnieszka Krawczyk-Łebek, Edyta Kostrzewa-Susłow   +8 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

On the Wireless Microwave Sensing of Bacterial Membrane Potential in Microfluidic-Actuated Platforms

Sensors, 2021
The investigation of the electromagnetic properties of biological particles in microfluidic platforms may enable microwave wireless monitoring and interaction with the functional activity of microorganisms.
Marc Jofre, Lluís Jofre, Luis Jofre-Roca   +2 more
doaj   +1 more source