Results 21 to 30 of about 12,231,174 (337)

A Protocol for Transverse Cardiac Slicing and Optical Mapping in Murine Heart

Frontiers in Physiology, 2019
Thin living tissue slices have recently emerged as a new tissue model for cardiac electrophysiological research. Slices can be produced from human cardiac tissue, in addition to small and large mammalian hearts, representing a powerful in vitro model ...
S. He, Q. Wen, C. O’Shea, R. Mu-u-min, K. Kou, A. Grassam-Rowe, Y. Liu, Z. Fan, X. Tan, X. Ou, P. Camelliti, D. Pavlovic, M. Lei, M. Lei   +13 more
doaj   +1 more source

Electrical Properties of Model Lipid Membranes

Membranes, 2022
Biological membranes are essential components of the living systems, and processes occurring with their participation are related mainly to electric phenomena such as signal transduction, existence of membrane potentials, and transport through the ...
Monika Naumowicz
doaj   +1 more source

An Evaluation of the Accuracy of Classical Models for Computing the Membrane Potential and Extracellular Potential for Neurons

Frontiers in Computational Neuroscience, 2017
Two mathematical models are part of the foundation of Computational neurophysiology; (a) the Cable equation is used to compute the membrane potential of neurons, and, (b) volume-conductor theory describes the extracellular potential around neurons.
Aslak Tveito, Aslak Tveito, Karoline H. Jæger, Glenn T. Lines, Łukasz Paszkowski, Joakim Sundnes, Joakim Sundnes, Andrew G. Edwards, Andrew G. Edwards, Tuomo Māki-Marttunen, Geir Halnes, Gaute T. Einevoll, Gaute T. Einevoll   +12 more
doaj   +1 more source

TREK2 Expressed Selectively in IB4-Binding C-Fiber Nociceptors Hyperpolarizes Their Membrane Potentials and Limits Spontaneous Pain

Journal of Neuroscience, 2014
Ongoing/spontaneous pain behavior is associated with ongoing/spontaneous firing (SF) in adult DRG C-fiber nociceptors (Djouhri et al., 2006). Causes of this SF are not understood. We show here that conducting (sometimes called uninjured) C-nociceptors in
C. Acosta, L. Djouhri, R. Watkins, Carol Berry, Kirsty Bromage, S. Lawson   +5 more
semanticscholar   +1 more source

The “Funny” Current (If) Inhibition by Ivabradine at Membrane Potentials Encompassing Spontaneous Depolarization in Pacemaker Cells

Molecules, 2012
Recent clinical trials have shown that ivabradine (IVA), a drug that inhibits the funny current (If) in isolated sinoatrial nodal cells (SANC), decreases heart rate and reduces morbidity and mortality in patients with cardiovascular diseases.
Y. Yaniv, V. Maltsev, B. Ziman, H. Spurgeon, E. Lakatta   +4 more
semanticscholar   +1 more source

On the physiological and cellular homeostasis of ascorbate

Cellular & Molecular Biology Letters, 2020
Recent interest in the role of ascorbate in crucial metabolic processes is driven by the growing number of medical reports that show beneficial effects of ascorbate supplementation for maintaining general well-being and recovery from a variety of medical
Magdalena Przybyło, Marek Langner
doaj   +1 more source

Different Roles of Membrane Potentials in Electrotaxis and Chemotaxis of Dictyostelium Cells

Eukaryotic Cell, 2011
Many types of cells migrate directionally in direct current (DC) electric fields (EFs), a phenomenon termed galvanotaxis or electrotaxis. The directional sensing mechanisms responsible for this response to EFs, however, remain unknown.
Runchi Gao, Xiao-Dong Zhang, Yao-Hui Sun, Y. Kamimura, A. Mogilner, P. Devreotes, Min Zhao   +6 more
semanticscholar   +1 more source

S6 peptide derived from KvAP channel shows cooperativity in gating on bilayer lipid membrane. [PDF]

PLoS ONE, 2013
Collective behavior of S6 peptide channels derived from KvAP (a bacterial potassium channel) incorporated in lipid bilayer membrane, has been investigated at various applied potentials through multi-channel electrophysiological experiments.
Chetan Malik, Subhendu Ghosh
doaj   +1 more source

The membrane potential of human platelets [PDF]

Blood, 1983
Abstract The membrane potential of the human platelet was investigated using the membrane potential probes 3,3′-dipropyl-2,2′-thiadicarbocyanine iodide and tritiated triphenylmethylphosphonium bromide. The membrane potential in physiologic buffer was estimated to be 52–60 mV inside negative.
Martin Sonenberg, Lawrence T. Friedhoff
openaire   +4 more sources

Motoneuron membrane potentials follow a time inhomogeneous jump diffusion process

Journal of Computational Neuroscience, 2011
Stochastic leaky integrate-and-fire models are popular due to their simplicity and statistical tractability. They have been widely applied to gain understanding of the underlying mechanisms for spike timing in neurons, and have served as building blocks ...
P. Jahn, Rune W. Berg, J. Hounsgaard, Susanne Ditlevsen   +3 more
semanticscholar   +1 more source