Results 31 to 40 of about 442,263 (324)

Depolarization of the conductance-voltage relationship in the NaV1.5 mutant, E1784K, is due to altered fast inactivation.

PLoS ONE, 2017
E1784K is the most common mixed long QT syndrome/Brugada syndrome mutant in the cardiac voltage-gated sodium channel NaV1.5. E1784K shifts the midpoint of the channel conductance-voltage relationship to more depolarized membrane potentials and ...
Colin H Peters, Alec Yu, Wandi Zhu, Jonathan R Silva, Peter C Ruben   +4 more
doaj   +1 more source

Oxidation-reduction and photophysical properties of isomeric forms of Safranin.

PLoS ONE, 2022
Safranine O is widely used in the bioenergetics community as an indicator dye to determine membrane potentials and as an electron transfer mediator in potentiometric titrations.
Eskil M E Andersen, Hsin Wang, Joshua S H Khoo, Jose F Cerda, Ronald L Koder   +4 more
doaj   +1 more source

Signature of a non-harmonic potential as revealed from a consistent shape and fluctuation analysis of an adherent membrane [PDF]

, 2014
The interaction of fluid membranes with a scaffold, which can be a planar surface or a more complex structure, is intrinsic to a number of systems - from artificial supported bilayers and vesicles to cellular membranes.
Bihr, Timo, Merkel, Rudolf, Monzel, Cornelia, Schmidt, Daniel, Seifert, Udo, Sengupta, Kheya, Smith, Ana-Sunčana   +6 more
core   +6 more sources

Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling

Nature Communications, 2016
‘Analogue’ modulation by somatic membrane potentials can modify ‘digital’ axonal action potentials. Here, the authors show that analogue modulation can occur in back-propagating dendritic action potentials and calcium signals, leading to signal ...
János Brunner, János Szabadics
doaj   +1 more source

Intrinsic Moment of Inertia of Membranes as bounds for the mass gap of Yang-Mills Theories [PDF]

, 2006
We obtain the precise condition on the potentials of Yang-Mills theories in 0+1 dimensions and D0 brane quantum mechanics ensuring the discretness of the spectrum. It is given in terms of a moment of inertia of the membrane. From it we obtain a bound for
A. Restuccia, A.J. Pérez, Bellorin, Boulton, Boulton, Claudson, de Wit, de Wit, de Wit, Gabadadze, Garcia del Moral, L. Navarro, Lüscher, M.P. Garcia del Moral, Mazy'a, Molchanov, Nicolai, Simon   +17 more
core   +1 more source

Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]

, 1977
The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner, B. Katz, E. Gergens, E. H. Lambert, F. Colomo, F. H. Norris, H. Ter�v�inen, J. I. Simpson, K. Koizumi, K. Ricker, M. A. Kamenskaya, M. A. Kamenskaya, M. Otsuka, P. Grafe, R. C. Scaer, S. D. Erulkar, S. J. Oh, U. Sonnhof, U. Sonnhof, W. C. Wiederholt   +19 more
core   +1 more source

Convulsant actions of 4-aminopyridine on the guinea-pig olfactory cortex slice [PDF]

, 1982
The effects of bath-applied 4-aminopyridine on neurones and extracellular potassium and calcium concentrations were recorded in slices of guinea-pig olfactory cortex. Neurones were orthodromically activated by stimulating the lateral olfactory tract.
Baranyi, Ben-Ari, Brismar, Brown, Buckle, Collins, Constanti, DiFrancesco, Dingemanse, Galvan, Galvan, Galvan, Gerrit Ten Bruggencate, Gilbey, Golenhofen, Halliwell, Heinemann, Jankowska, Jefferys, Kocsis, Lemeignan, Lipicky, Llinaś, Lundh, Martin Galvan, Matthews, McAfee, Mori, Neuman, Nicholson, Nicoll, Pelhate, Peter Grafe, Pichon, Scholfield, Scholfield, Schwartzkroin, Schwartzkroin, Sherratt, Shimahara, Spyker, Szente, Thesleff, Thompson, Ulbricht, von Haxthausen, Yanagisawa, Yeh   +47 more
core   +1 more source

Effects of lithium on electrical activity and potassium ion distribution in the vertebrate central nervous system [PDF]

, 1983
Three different regions of the vertebrate central nervous system maintained in vitro (frog spinal cord, guinea pig olfactory cortex and hippocampus) have been used to investigate how Li+ influences membrane potential, membrane resistance, action ...
Aldenhoff, Askenasi, Bruggencate, Czeh, Davidoff, Den Hertog, Duhm, G. Ten Bruggencate, Galvan, Giacobini, Goggans, Gorkin, Grafe, Grafe, Grafe, H. Emmert, Haas, Hullin, Israel, Janka, Kjeldsen, Koketsu, Krnjevic, Lee, M.M. Reddy, Myers, Nakajima, Nicoll, Obara, P. Grafe, Partridge, Paul, Reiser, Ritchie, Ritchie, Saneto, Smith, Sonnhof, Syková, Tang, Thomas, Thomas, Tilkian, Ullrich, Walz, Wraae   +45 more
core   +1 more source

Membrane Activity of Melittin and Magainin-I at Low Peptide-to-Lipid Ratio: Different Types of Pores and Translocation Mechanisms

Biomolecules
Antimicrobial peptides (AMPs) are believed to be a prominent alternative to the common antibiotics. However, despite decades of research, there are still no good clinical examples of peptide-based antimicrobial drugs for system application.
Marta V. Volovik, Oleg V. Batishchev
doaj   +1 more source

Descending Vasa Recta Endothelial Membrane Potential Response Requires Pericyte Communication. [PDF]

PLoS ONE, 2016
Using dual-cell electrophysiological recording, we examined the routes for equilibration of membrane potential between the pericytes and endothelia that comprise the descending vasa recta (DVR) wall.
Zhong Zhang, Kristie Payne, Thomas L Pallone   +2 more
doaj   +1 more source