Synapses with short-term plasticity are optimal estimators of presynaptic membrane potentials
Nature Neuroscience, 2010 The trajectory of the somatic membrane potential of a cortical neuron exactly reflects the computations performed on its afferent inputs. However, the spikes of such a neuron are a very low-dimensional and discrete projection of this continually evolving
Jean-Pascal Pfister +2 more
semanticscholar +1 more source
PLoS ONE, 2017 E1784K is the most common mixed long QT syndrome/Brugada syndrome mutant in the cardiac voltage-gated sodium channel NaV1.5. E1784K shifts the midpoint of the channel conductance-voltage relationship to more depolarized membrane potentials and ...
Colin H Peters +4 more
doaj +1 more source
Modulation of neural cell membrane conductance by the herbal anxiolytic and antiepileptic drug aswal [PDF]
, 2000 To evaluate the effects of aswal on ionic fluxes and neuronal excitation, we performed extracellular and whole cell patch clamp recordings on CA1 pyramidal neurons of guinea pigs and Long-Evans rats.
Grunze, Heinz +3 more
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A chloride channel in rat and human axons [PDF]
, 1991 Current recordings from single chloride channels were obtained from excised and cell-attached patches of rat and human axons. In rat axons the channels showed an outwardly rectifying current-voltage relationship with a slope conductance of 33 pS at ...
Baker +19 more
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Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling
Nature Communications, 2016 ‘Analogue’ modulation by somatic membrane potentials can modify ‘digital’ axonal action potentials. Here, the authors show that analogue modulation can occur in back-propagating dendritic action potentials and calcium signals, leading to signal ...
János Brunner, János Szabadics
doaj +1 more source
The double dipole model of theta rhythm generation: Simulation of laminar field potential profiles in dorsal hippocampus of the rat [PDF]
, 1982 A set of compartmental models of CA1 pyramidal, granular and polymorph cells of the dorsal hippocampus have been used to simulate membrane potentials generated by synaptic activation at various levels along these cells.
Boer, J. +3 more
core +2 more sources
Particle transport across a channel via an oscillating potential [PDF]
, 2017 Membrane protein transporters alternate their substrate-binding sites between the extracellular and cytosolic side of the membrane according to the alternating access mechanism.
Dagdug, Leonardo +4 more
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Descending Vasa Recta Endothelial Membrane Potential Response Requires Pericyte Communication. [PDF]
PLoS ONE, 2016 Using dual-cell electrophysiological recording, we examined the routes for equilibration of membrane potential between the pericytes and endothelia that comprise the descending vasa recta (DVR) wall.
Zhong Zhang +2 more
doaj +1 more source
Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]
, 2004 The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model.
Chow C C +17 more
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MEMBRANE POTENTIALS AND CATAPHORETIC POTENTIALS OF PROTEINS [PDF]
Journal of General Physiology, 1923 1. It has been shown in preceding publications that the membrane potentials of protein solutions or gels are determined by differences in the concentration of a common ion (e.g. hydrogen ion) inside a protein solution or protein gel and an outside aqueous solution free from protein, and that the membrane potentials can be calculated with a good degree ...
openaire +3 more sources