Results 41 to 50 of about 228,598 (287)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Detection of Membrane Potential in Mycobacterium tuberculosis

open access: yesBio-Protocol, 2013
DiOC2 (Novo et al., 2000) exhibits green fluorescence in all bacterial cells, but the fluorescence shifts towards red emission as the dye molecules self associate at the higher cytosolic concentrations caused by larger membrane potentials.
Manbeena Chawla, Amit Singh
doaj   +1 more source

The Impact of Anomalous Diffusion on Action Potentials in Myelinated Neurons

open access: yesFractal and Fractional, 2021
Action potentials in myelinated neurons happen only at specialized locations of the axons known as the nodes of Ranvier. The shapes, timings, and propagation speeds of these action potentials are controlled by biochemical interactions among neurons ...
Corina S. Drapaca
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Non-linear population firing rates and voltage sensitive dye signals in visual areas 17 and 18 to short duration stimuli. [PDF]

open access: yesPLoS ONE, 2008
Visual stimuli of short duration seem to persist longer after the stimulus offset than stimuli of longer duration. This visual persistence must have a physiological explanation.
David Eriksson   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Effects of beauvericin on root cell transmembrane electric potential, electrolyte leakage and respiration of maize roots with different susceptibility to Fusarium

open access: yesPlant, Soil and Environment, 2006
Effect of beauvericin on root cell transmembrane electric potential (EM), electrolyte leakage and respiration of roots were studied in two maize cultivars (Zea mays L.) with different susceptibility to this toxigenic metabolite produced by Fusarium ...
J. Pavlovkin   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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