Results 151 to 160 of about 3,087,877 (362)

Autoinhibition of TRPV6 Channel and Regulation by PIP2

iScience, 2020
Summary: Transient receptor potential vanilloid 6 (TRPV6), a calcium-selective channel possessing six transmembrane domains (S1-S6) and intracellular N and C termini, plays crucial roles in calcium absorption in epithelia and bone and is involved in ...
Ruiqi Cai, Xiong Liu, Rui Zhang, Laura Hofmann, Wang Zheng, Md Ruhul Amin, Lingyun Wang, Qiaolin Hu, Ji-Bin Peng, Marek Michalak, Veit Flockerzi, Declan W. Ali, Xing-Zhen Chen, Jingfeng Tang   +13 more
doaj  

Characterization and cloning of fasciclin I and fasciclin II glycoproteins in the grasshopper [PDF]

, 1988
Monoclonal antibodies were previously used to identify two glycoproteins, called fasciclin I and II (70 and 95 kDa, respectively), which are expressed on different subsets of axon fascicles in the grasshopper (Schistocerca americana) embryo.
Bastiani, Michael J., Goodman, Corey S., Harrelson, Allan L., Makk, George, McAllister, Linda, Schilling, Jim, Snow, Peter M., Zinn, Kai   +7 more
core  

A Spectrographic Analysis of Two Protein Fractions of the Fat-Globule Membrane of Normal Cow's Milk

, 1957
C.T. Herald, J.R. Brunner, S.T. Bass
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Effects of Phenobarbital on the Synthesis and Degradation of the Protein Components of Rat Liver Microsomal Membranes

, 1969
Yoshiaki Kuriyama, T Omura, Philip Siekevitz, George E. Palade   +3 more
openalex   +1 more source

Preparation and Use of Membrane Electrodes of Basic Salts of Deaminated Proteins for Determination of Cation Activities of Electrolytic Solutions. Part I. Deaminated Ovalbumin [PDF]

, 1964
D. R. Pandit, C. S. Narwani
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Na⁺,K⁺-ATPase with Disrupted Na⁺ Binding Sites I and III Binds Na⁺ with Increased Affinity at Site II and Undergoes Na⁺-Activated Phosphorylation with ATP

Biomolecules
Na+,K+-ATPase actively extrudes three cytoplasmic Na+ ions in exchange for two extracellular K+ ions for each ATP hydrolyzed. The atomic structure with bound Na+ identifies three Na+ sites, named I, II, and III.
Hang N. Nielsen, Rikke Holm, Ryan Sweazey, Jens Peter Andersen, Pablo Artigas, Bente Vilsen   +5 more
doaj   +1 more source

High-affinity binding sites involved in the import of porin into mitochondria [PDF]

, 1987
The specific recognition by mitochondria of the precursor of porin and the insertion into the outer membrane were studied with a radiolabeled water-soluble form of porin derived from the mature protein.
Neupert, Walter, Pfaller, Rupert
core   +1 more source

Dissolution of erythrocyte membranes in water and comparison of the membrane protein with other structural proteins.

, 1968
Daniel Mazia, A L Ruby
openalex   +1 more source