Results 341 to 350 of about 9,896,950 (388)
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1992
MCP serves to down-regulate the activation of complement on host tissue. It performs this function by serving as a cofactor for the factor I-mediated cleavage of C3b and C4b. MCP is most likely an intrinsic regulator, i.e., it primarily protects its home cell.
M K, Liszewski, J P, Atkinson
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MCP serves to down-regulate the activation of complement on host tissue. It performs this function by serving as a cofactor for the factor I-mediated cleavage of C3b and C4b. MCP is most likely an intrinsic regulator, i.e., it primarily protects its home cell.
M K, Liszewski, J P, Atkinson
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Chemistry and Physics of Lipids, 1972
I RECENTLY summarized X-ray diffraction data from some natural membranes to show that the original Danielli-Davson model is not valid for them1. A second widely-discussed structural model, having protein inserted into a lipid bilayer, was put forward as an alternative.
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I RECENTLY summarized X-ray diffraction data from some natural membranes to show that the original Danielli-Davson model is not valid for them1. A second widely-discussed structural model, having protein inserted into a lipid bilayer, was put forward as an alternative.
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Microseparation of membrane proteins
Journal of Separation Science, 2009AbstractMembrane proteins are generally of natural low abundance and insoluble to aqueous solutions. Thus, investigation of membrane proteins is relatively hampered since efficient separation of membrane proteins are rather challenging. Microseparation approaches certainly play an essential role in fulfilling such demanding investigations due to their ...
Zhaowei, Zhang +4 more
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Trends in Biotechnology, 1997
Membrane proteins perform many of the essential functions required for life. They are often the targets of medicinal drugs and have many potential uses in biotechnological processes. Therefore our ability to understand them and manipulate their functions is both important and necessary to enable protein engineers to create 'designer' membrane proteins (
I, Mingarro, G, von Heijne, P, Whitley
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Membrane proteins perform many of the essential functions required for life. They are often the targets of medicinal drugs and have many potential uses in biotechnological processes. Therefore our ability to understand them and manipulate their functions is both important and necessary to enable protein engineers to create 'designer' membrane proteins (
I, Mingarro, G, von Heijne, P, Whitley
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Membrane phosphoinositides and protein–membrane interactions
Amino Acids, 2013Proteins with polybasic clusters bind to negatively charged phosphoinositides at the cell membrane. In this review, I have briefly discussed the types of phosphoinositides naturally found on membrane surfaces and how they recruit protein complexes for carrying out the process of signal transduction.
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Membrane Transport of Proteins
Nature New Biology, 1972FACILITATED diffusion of small organic molecules across cell membranes is thought to be carrier-mediated in part because the process displays reaction kinetics. Models describing carrier transport assume that the transported molecule is associated with the membrane, reacting presumably with membrane proteins, and is then moved across the barrier.
C, Liebow, S S, Rothman
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Lipid Membranes for Membrane Proteins
2014The molecular dynamics (MD) simulation of membrane proteins requires the setup of an accurate representation of lipid bilayers. This chapter describes the setup of a lipid bilayer system from scratch using generally available tools, starting with a definition of the lipid molecule POPE, generation of a lipid bilayer, energy minimization, MD simulation,
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The cell membrane and membrane proteins
2018This chapter talks about biological membranes that have a lipid bilayer structure made up of a variety of different lipids held together by noncovalent bonds. It shows that lipids are arranged with their hydrophobic tails pointing to the middle of the bilayer and their hydrophilic sections to the outside.
Despo Papachristodoulou +3 more
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Journal of Chemical Information and Computer Sciences, 2001
Integral membrane proteins play important roles in living cells. Due to difficulties of experimental techniques, theoretical approaches, i.e., topology prediction methods, are important for structure determination of this class of proteins. Here we show a detailed comparison of transmembrane topology prediction methods. According to this comparison, we
G E, Tusnády, I, Simon
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Integral membrane proteins play important roles in living cells. Due to difficulties of experimental techniques, theoretical approaches, i.e., topology prediction methods, are important for structure determination of this class of proteins. Here we show a detailed comparison of transmembrane topology prediction methods. According to this comparison, we
G E, Tusnády, I, Simon
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Crystallization of Membrane Proteins
2013The crystallization of membrane proteins is an essential technique for the determination of atomic models of three-dimensional structures by X-ray crystallography. The compositions of solutions of purified membrane proteins are altered, so as to transiently induce supersaturation, a requirement for crystal nucleation and growth.
Florian G, Müller, C Roy D, Lancaster
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