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Proteins of the synaptic membrane

Neurochemical Research, 1977
The purpose of this communication is to provide a survey of contempory information concerning the composition, disposition, and functional significance of proteins in or on synaptic membranes derived from rat brain synaptosomes. Special emphasis is placed on their content of glycoproteins, fibrous proteins, proteins susceptible to rapid phosphorylation
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Membrane Proteins

European Lisp Symposium, 2021
Reinhart AF Reithmeier
semanticscholar   +1 more source

Structures of membrane proteins

The Journal of Membrane Biology, 1978
The possible conformations of integral membrane proteins are restricted by the nature of their environment. In order to satisfy the requirement of maximum hydrogen bonding, those portions of the polypeptide chain which are in contact with lipid hydrocarbon must be organized into regions of regular secondary structure.
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Membrane Protein Solubilization

2009
A critical step in any in vitro analysis of membrane proteins is the solubilization of the membrane to extract the protein of interest in an active form to obtain an aqueous solution containing the membrane protein complexed with detergents and lipids in a form suitable for purification and further analysis. This process is particularly delicate as the
Katia, Duquesne, James N, Sturgis
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Membrane protein complexes

Current Opinion in Structural Biology, 2002
A wide range of membrane protein structures have been published during the past two years. These have included proteins from both eucaryotic and heterologously overexpressed sources. Whereas some of these proteins were crystallised using conventional techniques, others employed the new methods of lipidic cubic phase crystallisation and antibody ...
Bernadette, Byrne, So, Iwata
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Proteomics of Membrane Proteins

2003
Publisher Summary The chapter focuses on the proteomics of the membrane proteins. As an increasing number of genomes are sequenced and a growing number of membrane proteins are identified, the gap in knowledge about the structure and function of these proteins is likely to increase. Moreover, in the post-genomic era, with proteomics emerging as a new
Julian P, Whitelegge   +2 more
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Bioinformatics of Membrane Proteins

2002
As for all proteins, there are three basic problems facing bioinformatics in the field of membrane proteins: to reliably identify membrane proteins in genome-wide data sets, to predict as much as possible about their structure, and to predict as much as possible about their function.
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Membrane proteins Membrane protein structure

Current Opinion in Structural Biology, 1996
J E, Walker, M, Saraste
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Membrane-protein topology

Nature Reviews Molecular Cell Biology, 2006
In the world of membrane proteins, topology defines an important halfway house between the amino-acid sequence and the fully folded three-dimensional structure. Although the concept of membrane-protein topology dates back at least 30 years, recent advances in the field of translocon-mediated membrane-protein assembly, proteome-wide studies of membrane ...
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A method for detergent-free isolation of membrane proteins in their local lipid environment

Nature Protocols, 2016
Sarah C. Lee   +10 more
semanticscholar   +1 more source

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