Results 181 to 190 of about 262,474 (307)

Revisiting the role of Annexins in membrane trafficking. [PDF]

Cell Mol Life Sci
Grewal T, Gerke V, Nylandsted J, Rentero C, Enrich C.   +4 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

When two worlds collide: actin dynamics on endomembranes regulates membrane trafficking. [PDF]

Curr Opin Cell Biol
Marchan MF, Bear JE.
europepmc   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

Advanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Wenchao Hu, Siying Fei, Miao Xu, Taoyuan Yang, Ruilong Xia, Ting Wen, Fengting Zhu, Yan Fu, Yang Li, Wei Xia, Ran Qian, Yuanying Liu, Zhicheng Tian, Lamei Li, Qian Zhou, Lize Xiong, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou‐Gang Xie, Changgeng Peng   +27 more
wiley   +1 more source

Iron modulates the membrane-binding and the intracellular trafficking of 5-lipoxygenase: functional implications in neurodegeneration

, 2015
Iron modulates the membrane-binding and the intracellular trafficking of 5-lipoxygenase: functional implications in neurodegeneration Beatrice Dufrusine1, Andrea Di Francesco1, Annalaura Sabatucci1, Clotilde Beatrice Angelucci2, Sergio Oddi2,3, Claudio ...
SABATUCCI, Annalaura, Mauro, Maccarrone, ODDI, Sergio, DUFRUSINE, BEATRICE, Dieter, Steinhilber, DI FRANCESCO, ANDREA, DAINESE, Enrico, ANGELUCCI, Clotilde, D'ADDARIO, Claudio   +8 more
core  

MYO1B in human disease: an actin-based motor linking membrane trafficking to oncogenic signaling, metastasis, and vascular aging. [PDF]

Front Oncol
Li Y, Zhang J, Gao X, Zhou F, Chen T, Zhao W, Li X, Zhang Y.   +7 more
europepmc   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Membrane trafficking

FEBS Letters, 2007
openaire   +1 more source

Regulation of Membrane Trafficking [PDF]

Cell, 1999
Gonzalez Jr., Lino, Scheller, Richard H
openaire   +1 more source

Pathogen-induced rerouting of host membrane trafficking. [PDF]

Curr Opin Cell Biol
Woida PJ, Lamason RL.
europepmc   +1 more source