Results 181 to 190 of about 398,965 (304)

Pathogen-induced rerouting of host membrane trafficking. [PDF]

Curr Opin Cell Biol
Woida PJ, Lamason RL.
europepmc   +1 more source

Mechanisms for regulation of RAS palmitoylation and plasma membrane trafficking in hematopoietic malignancies. [PDF]

J Clin Invest, 2023
Yu F, Qian Z.
europepmc   +1 more source

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

Advanced Science, EarlyView.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao, Zhan Shi, Peng Hu, Changping Wang, Hui Wang   +4 more
wiley   +1 more source

Flotillins in membrane trafficking and physiopathology. [PDF]

Biol Cell
Bodin S, Elhabashy H, Macdonald E, Winter D, Gauthier-Rouvière C.   +4 more
europepmc   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Identification of a RAB32-LRMDA-Commander membrane trafficking complex reveals the molecular mechanism of human oculocutaneous albinism type 7. [PDF]

Nat Commun
Butkovič R, Healy MD, de Heus C, Walker AP, Beyers W, McNally KE, Lewis PA, Heesom KJ, Liv N, Klumperman J, Di Pietro S, Collins BM, Cullen PJ.   +12 more
europepmc   +2 more sources

The autotaxin-LPA axis promotes membrane trafficking and secretion in yolk sac visceral endoderm cells. [PDF]

Biol Open, 2023
Koike S, Keino-Masu K, Tanimoto Y, Takahashi S, Masu M.   +4 more
europepmc   +1 more source

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

LEAP2 triggers retromer-mediated membrane trafficking of MOSPD2 to promote chemotaxis in teleost monocytes/macrophages. [PDF]

Zool Res
Zhu TF, Zhao ZY, Fei CJ, Shen SC, Shao JZ, Nie L, Chen J.   +6 more
europepmc   +1 more source

Imaging of post-synaptic membrane trafficking in neuronal dendrites: progress, limitations, and new developments. [PDF]

Neurophotonics, 2023
Perrais D, Sposini S, Angibaud J.
europepmc   +1 more source