Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Next-Generation Nafion Membranes: Synergistic Enhancement of Electrochemical Performance and Thermomechanical Stability with Sulfonated Siliceous Layered Material (sSLM). [PDF]
Loise V, Simari C.
europepmc +1 more source
Cultivation of Cellulose-splitting Bacteria on Membranes of Acetobacter xylinum
M. Aschner
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Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Amorphous/crystalline HTiNbO<sub>5-X</sub> membranes for efficient confined flow synthesis of acetate ester flavours. [PDF]
Fang Z+9 more
europepmc +1 more source
THE DIFFUSION OF WATER INTO LECITHIN-COLLODION MEMBRANES
Harold A. Abramson, S. Gray
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AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou+5 more
wiley +1 more source
Layer-by-Layer Assembled Nanocomposite Membranes with Functionalized Dendritic Mesoporous Silica Nanoparticles for Selective Heavy Metal Removal. [PDF]
Alotaibi KM+5 more
europepmc +1 more source
THE EFFECT OF DENERVATION ON THE ACTION OF SYMPATHOMIMETIC AMINES ON THE NICTITATING MEMBRANE [PDF]
A. Fleckenstein, J. H. Burn
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