Results 51 to 60 of about 75,950 (286)

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

open access: yesAdvanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang   +8 more
wiley   +1 more source

Editorialising practices, competitive marketablility and James Thomson's 'The seasons' [PDF]

open access: yes, 2015
The lapse of Andrew Millar's copyright for James Thomson's The Seasons in 1765 resulted in an increasing number of new editions of the poem being published in the late eighteenth century.
Van De Walle, Kwinten
core  

VAE+DDPG: An Attention‐Enhanced Variational Autoencoder for Deep Reinforcement Learning‐Based Autonomous Navigation in Low‐Light Environments

open access: yesAdvanced Intelligent Systems, EarlyView.
Variational Autoencoder+Deep Deterministic Policy Gradient addresses low‐light failures of infrared depth sensing for indoor robot navigation. Stage 1 pretrains an attention‐enhanced Variational Autoencoder (Convolutional Block Attention Module+Feature Pyramid Network) to map dark depth frames to a well‐lit reconstruction, yielding a 128‐D latent code ...
Uiseok Lee   +7 more
wiley   +1 more source

On the Prospects for African Philosophy in Australia

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT This paper grapples with the situation of people of African descent in Australia by working through the constitution of the body of academic philosophy in the country. It contends with the parochialism of the Australian philosophical community and the prospects for the cultivation of greater pluralism. Taking African philosophy as one possible
Bryan Mukandi
wiley   +1 more source

Appropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park   +9 more
wiley   +1 more source

The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model

open access: yesAnnals of Neurology, EarlyView.
Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins   +104 more
wiley   +1 more source

Contemporary ukrainian literature and the myth of Donbass. Fictional and critical representations in the francophone area

open access: yesАктуальні питання суспільних наук та історії медицини
Research Objective. The aim of this work is to demonstrate that contemporary Ukrainian literature is now an integral part of the European intellectual space as a legitimate object of aesthetic and political reflection. In 2020-2024, translations of this
Світлана Наместюк   +3 more
doaj   +1 more source

Reunion and reconciliation, reviewed and reconsidered [PDF]

open access: yes, 2016
At the close of the Civil War in 1865, many Americans began talking about “reunion” and “reunification,” even “healing” and “reconciliation,” although the precise meaning of those words would remain elusive.
Silber, N.
core  

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura   +14 more
wiley   +1 more source

Tangihanga: The ultimate form of Māori cultural expression - overview of a research programme [PDF]

open access: yes, 2010
Death, observed through the process of tangihanga (time set aside to grieve and mourn, rites for the dead) or tangi (to grieve and mourn), is the ultimate form of Māori cultural expression.
Maxwell, Te Kahautu   +7 more
core  

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