Results 231 to 240 of about 110,606 (306)

Erwin Schrödinger und die Versuchungen der (Wissenschafts‐)Biografik: Vorurteilsgefüge und Mechanismen der Skandalisierung

open access: yesBerichte zur Wissenschaftsgeschichte, EarlyView.
Since late 2021, serious allegations have been made against physicist Erwin Schrödinger, ranging from pedophilia to serial sexual abuse. These accusations have significantly tarnished the Nobel Prize winner's public reputation. The ongoing debate has repeatedly raised the question of whether, and to what extent, these grave allegations are justified ...
Magdalena Gronau, Martin Gronau
wiley   +1 more source

Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek   +3 more
wiley   +1 more source

Discovery of CRBN‐based molecular glue degraders targeting WIZ transcription factor

open access: yesBulletin of the Korean Chemical Society, EarlyView.
This work reports the discovery of 9l, a novel cereblon‐based molecular glue degrader which targets the WIZ transcription factor. Compound 9l facilitates WIZ‐CRBN ternary complex formation to degrade WIZ, subsequently inducing γ‐globin expression in HUDEP‐2 cells and highlighting its potential as a sickle cell disease therapy.
Tae‐Jun Kim   +8 more
wiley   +1 more source

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

open access: yesBMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu   +5 more
wiley   +1 more source

Profiling cell proliferation after whole-genome duplication in human cells. [PDF]

open access: yesBiol Open
Yang G   +7 more
europepmc   +1 more source

Family Involvement and Financial Performance: How Do They Affect the Sustainability Commitment of Family Businesses?

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The socio‐emotional wealth (SEW) perspective suggests that the specific priorities of a family business may make it more or less inclined to engage in sustainable practices. This paper examines how family business heterogeneity regarding family ownership, financial performance, and family board members affects the sustainability commitment of ...
Sonia Sánchez‐Andújar   +2 more
wiley   +1 more source

Market and Nonmarket Strategies in Focus: How Entrepreneurs Tackling the Grand Challenge of Waste Management Navigate Institutional and Market Adversity in Ghana

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Waste management remains a critical grand challenge in African countries. While entrepreneurship has been a viable strategy for addressing this challenge, it is fraught with constraints. This study investigates the strategies orchestrated by entrepreneurs to navigate adversity in Waste management and ensure the social and economic viability of
Tahiru Azaaviele Liedong   +3 more
wiley   +1 more source

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