Results 101 to 110 of about 1,079 (230)

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang   +13 more
wiley   +1 more source

Perspectives on Identity, Migration, and Displacement

open access: yes, 2013
Perspectives on Identity, Migration, and Displacement -- edited by Steven Tötösy de Zepetnek, I-Chun Wang, and Hsiao-Yu Sun (Kaohsiung: National Sun Yat-sen University Press, 2010.
Sun, Hsiao-Yu   +2 more
core  

Consensus Formation and Change are Enhanced by Neutrality

open access: yesAdvanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag   +3 more
wiley   +1 more source

Homeplaces: photography, migration and memory

open access: yes
DCU Intergenerational Learning Programme, in partnership with Photowings and the University of Northampton, have started an ILP-led project on the topic of family albums and a sense of place, Homeplaces.
Leet, Sri-Kartini   +3 more
core  

Pholidota‐Inspired Electronic Skin Possessing Terahertz‐Wave Reflection–Absorption–Transmission Switchability

open access: yesAdvanced Science, EarlyView.
The pholidota‐inspired electronic skin is successfully constructed, originally realized four‐state reversible switching of terahertz‐wave reflection, absorption, transmission, and secondary reflection. In response to external demands, it issues deformation instructions, verifies the deformation state after the equipment executes the action, and thus ...
Shangjing Li   +4 more
wiley   +1 more source

Creative engagement with migration - Special issue of Crossings: Journal of Migration & Culture, v.10(1)

open access: yes, 2019
The course of cultures at both local and global levels is crucially affected by migratory movements. In turn, culture itself is turned migrant. This journal will advance the study of the plethora of cultural texts on migration produced by an increasing ...
Jeffery, L.   +3 more
core  

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

Cultural representations of Italians in Wales (1920s-2010s) [PDF]

open access: yes
This thesis aims to enrich academic scholarship by investigating cultural narratives of Italians in Wales from 1920s–2010s. It will make use of sources that have been understudied, such as the photographs of Italians in Wales during the interwar period ...
Chezzi, Bruna
core  

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou   +12 more
wiley   +1 more source

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