Results 81 to 90 of about 61,156 (193)

Natural History of Alternaria Sensitisation and Association With Asthma and Rhinitis From Childhood to Adulthood

open access: yesAllergy, EarlyView.
We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...
Mohammad Leily   +7 more
wiley   +1 more source

A systematic approach to standardizing the visual appearance of endometriotic lesions for artificial intelligence recognition

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
A visual ontology of endometriotic lesions designed for artificial intelligence recognition: back to the past to shape the future. This study proposes a standardized visual ontology of endometriosis lesions observed during laparoscopy, based on a systematic search of the literature.
Antoine Netter   +16 more
wiley   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

open access: yesBrain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen   +8 more
wiley   +1 more source

Artificial Intelligence (AI) Impact on Dental Education and Curriculum: A Systematic Review Following PRISMA Guidelines

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Importance AI technologies increasingly influence dental education, but their instructional value, stakeholder perspectives, and institutional implications require further study. Objective To synthesise evidence on AI's impact in undergraduate dental education, focusing on learning outcomes, stakeholder perspectives, and curriculum design ...
Laura Reyes‐Alardo   +7 more
wiley   +1 more source

Project Sickle Cure: A Prospective, International Observational Study of Hematopoietic Cell Transplantation for Sickle Cell Disease

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic and life‐limiting hemoglobin and systemic vascular disease. While over 1000 people have undergone hematopoietic cell transplantation (HCT) over the last 40 years, long‐term disease‐specific and health‐related quality of life data are lacking.
Gregory M. T. Guilcher   +20 more
wiley   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

open access: yesThe FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati   +4 more
wiley   +1 more source

Updates and controversies in contemporary grading of clear cell renal cell carcinoma and papillary renal cell carcinoma

open access: yesHistopathology, EarlyView.
New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner   +4 more
wiley   +1 more source

Never Mind the Bollards: Exploring the Role of GCHQ, MI5, and the National Technical Authorities in UK Security Markets

open access: yesThe Howard Journal of Crime and Justice, EarlyView.
ABSTRACT The cultures and governance of security markets in the United Kingdom are often characterised through a paradoxical narrative of simultaneous state retreat and progressive advance. In the face of repeated recent high‐profile security failures, and global changes in material political economy, we argue that UK security governance is adapting to
Ben Collier, Jamie Buchan
wiley   +1 more source

BLIMP‐1 and CD39 expression define human effector memory regulatory T cells in blood and recall responses to viruses

open access: yesImmunology &Cell Biology, EarlyView.
This study found that BLIMP‐1 is highly expressed in activated effector/memory human regulatory T cells, especially CD39+ Tregs, where it is associated with increased IL‐10 production and a conserved phenotype across blood and lung tissues during immune responses such as SARS‐CoV‐2 infection.
Chansavath Phetsouphanh   +10 more
wiley   +1 more source

The Effects of Regulatory Office Closures on Bank Behavior

open access: yesJournal of Money, Credit and Banking, EarlyView.
Abstract We investigate if the decentralized structure of regulatory office networks influences supervisory outcomes and bank behavior. Following the closure of an office, banks previously supervised by that office increase their lending and risk‐taking.
IVAN LIM, JENS HAGENDORFF, SETH ARMITAGE
wiley   +1 more source

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