Results 91 to 100 of about 235,895 (350)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Homogenization on Multi-Materials’ Elements: Application to Printed Circuit Boards and Warpage Analysis

MATEC Web of Conferences, 2016
Multi-material domains are often found in industrial applications. Modelling them can be computationally very expensive due to meshing requirements. The finite element properties comprising different materials are hardly accurate.
Araújo Manuel, Alves J. L., Silva Paulo, Delgado Pedro   +3 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Nonlinear distortion of nonreciprocal transmission in parity-time-symmetric silicon micromechanical resonators

Microsystems & Nanoengineering
Parity-time (PT) symmetric resonators have an exact phase with real frequency eigenvalues and a broken phase with complex-conjugate frequency eigenvalues.
Rui Wang, Lei Han, Man-Na Zhang, Li-Feng Wang, Qing-An Huang   +4 more
doaj   +1 more source

Integrated Bidirectional Inductive-Array Design for Power Transfer in Implantable BioMEMS

Proceedings, 2019
This work presents a novel design of a bidirectional Inductive Power Transfer (IPT) system capable of continuous monitoring of cardiac pressure. The proposed system results from a robust electromagnetic coupling between an external reading coil and an ...
Natiely Hernández-Sebastián, Francisco Javier Renero-Carrillo, Daniela Díaz-Alonso, Wilfrido Calleja-Arriaga   +3 more
doaj   +1 more source

Casimir attractive-repulsive transition in MEMS

, 2012
Unwanted stiction in micro- and nanomechanical (NEMS/MEMS) systems due to dispersion (van der Waals, or Casimir) forces is a significant hurdle in the fabrication of systems with moving parts on these length scales.
Boström, M., Brevik, I., Dou, M., Ellingsen, S. Å., Persson, C., Sernelius, Bo E.   +5 more
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Enhanced sensitivity in nonlinear parity-time symmetric silicon micromechanical resonators

Microsystems & Nanoengineering
Silicon resonant sensors are essential to a wide range of applications that involve the detection of pressure, acceleration, and magnetic fields.
Yu-Jue Xie, Li-Feng Wang, Man-Na Zhang, Rui Wang, Qing-An Huang   +4 more
doaj   +1 more source

Temperature Dependence of Viscosity in Normal Fluid $^3$He Below 800mK Determined by a Micro-electro-mechanical Oscillator

, 2016
A micro-electro-mechanical system vibrating in its shear mode was used to study the viscosity of normal liquid $^3$He from 20mK to 770mK at 3bar, 21bar, and 29bar.
Barquist, C. S., Chan, H. B., Gonzalez, M., Jiang, W. G., Lee, Y., Zheng, P.   +5 more
core   +2 more sources

Unlocking the Power of Quercetin‐Encapsulated Mesoporous Bioactive Glass Nanoparticles: A Multifunctional Approach to Bone Regeneration

Advanced Engineering Materials, EarlyView.
Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello, Qaisar Nawaz, Pier Francesco Ferrari, Laura Pastorino, Roberto Raiteri, Aldo R. Boccaccini   +5 more
wiley   +1 more source