Results 111 to 120 of about 73,923,876 (280)

Human papillomavirus and vaccine-related perceptions among men who have sex with men: a systematic review

, 2013
Background Targeted human papillomavirus (HPV) vaccine could prevent HPV-related cancers and genital warts among men who have sex with men (MSM). In order to develop effective vaccination programmes for MSM, it is crucial to understand their knowledge ...
Nadarzynski, T., Helen Smith (19020), Jones, Christina, Smith, H., Richardson, D., Smith, Helen, Richardson, Daniel, Llewellyn, Carrie, Jones, C.J., Nadarzynski, Tomasz, Daniel Richardson (718112), Llewellyn, C.D., Christina Jones (660931), Christina J Jones (16046195), Carrie Llewellyn (4461832), Tom Nadarzynski (5102480)   +15 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Perceptions of HPV and attitudes towards HPV vaccination amongst men who have sex with men: A qualitative analysis

, 2017
Objectives: Men who have sex with men (MSM) are at risk of genital warts and anal cancer due to human papillomavirus (HPV) infection. This study explores MSMs’ perceptions of HPV and HPV vaccination prior to the introduction of this programme.Design ...
Nadarzynski, T., Helen Smith (19020), Smith, H., Richardson, D., Carrie Llewellyn, Smith, Helen, Richardson, Daniel, Pollard, Alex, Llewellyn, Carrie, Daniel Richardson, Nadarzynski, Tomasz, Daniel Richardson (718112), Llewellyn, C.D., Helen Smith, Alex Pollard, Carrie Llewellyn (4461832), Tom Nadarzynski (5102480), Alex Pollard (6729461), Pollard, A., Tom Nadarzynski   +19 more
core   +1 more source

Safer sex practices among newly diagnosed HIV-positive men who have sex with men in China: results from an ethnographic study

International Journal of Qualitative Studies on Health & Well-Being, 2017
The study reported here sought to understand the rationales of safer sex practices adopted by newly diagnosed HIV-positive men who have sex with men (MSM).
Haochu Li, Andrea Sankar, Eleanor Holroyd, Baofa Jiang   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Determinants of HIV/AIDS Prevention Behavior Among Men Who Have Sex with Men: A Mixed-Methods Study in Palu, Indonesia

Public Health of Indonesia
Background: Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) remain global health challenges, particularly among men who have sex with men (MSM), who face biological and social vulnerabilities.
Rasyika Nurul Fadjriah, Khairunnisaa, Mu’minsyah, Adhar Arifuddin, Abd Rahman   +4 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Men who have sex with men (MSM) in Iloilo City, Philippines: Profile, sexual history, level of knowledge about HIV/AIDS and sexual risk-taking behaviors [PDF]

, 2014
Journal articleThis study was conducted to determine the sociodemographic profile, sexual history, level of knowledge about HIV/AIDS and sexual risk-taking behaviors of men who have sex with men (MSM) in Iloilo City.
Italia, William Fred P., Oducado, Ryan Michael F.   +1 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source