Results 321 to 330 of about 236,698 (345)

Mendelian Randomization

JAMA, 2017
Confounding and reverse causality have prevented us from drawing meaningful clinical interpretation even in well-powered observational studies. Confounding may be attributed to our inability to randomize the exposure variable in observational studies. Mendelian randomization (MR) is one approach to overcome confounding.
Connor A, Emdin   +2 more
openaire   +4 more sources

Mendelian Genetics

2022
This chapter examines the study of Mendelian genetics. It shows how genetically determined traits are transmitted in sexually reproducing eukaryotes from one generation to the next. It then considers the organization of genes and chromosomes in sexually reproducing eukaryotes.
Jon Scott   +9 more
openaire   +1 more source

Mendelian Randomization

Cold Spring Harbor Perspectives in Medicine, 2021
Mendelian randomization borrows statistical techniques from economics to allow researchers to analyze the effects of the environment, drug treatments, and other factors on human biology and disease. Taking advantage of the fact that genetic variation is randomized among children from the same parents, it allows genetic variants known to influence ...
openaire   +2 more sources

Mendelian Puzzles

Science, 2012
Variations that lie outside of the coding region of a mutated gene can give rise to a range of clinical phenotypes for a Mendelian genetic disorder.
Ashish Kapoor, Aravinda Chakravarti
openaire   +3 more sources

Mendelian and non-Mendelian heredity: a reappraisal

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1966
The first report of a non-Mendelian gene (Correns 1908) appeared just eight years after the rediscovery of Mendel’s laws and, in this sense, Mendelian and non-Mendelian heredity have both been available for analysis and comparison for almost sixty years.
openaire   +3 more sources

On the origins of the Mendelian laws

Journal of Heredity, 1984
The two laws usually attributed to Mendel were not considered as laws by him. The first law, the law of independent segregation occurs in Mendel's paper as an assumption or hypothesis. Hugo de Vries refers to this as a law discovered by Mendel. This appears to be the first use of an expression equivalent to Mendel's law.
Alain F. Corcos, Floyd V. Monaghan
openaire   +3 more sources

Mendelian Phenotypes in the Netherlands

Human Heredity, 1993
We report here a database listing Mendelian phenotypes described in the Netherlands and/or in populations originating from this country, and describe the results of a quantitative analysis of the database. The database is specifically directed at the presence, frequency and origin of the phenotypes.
L.P. ten Kate, J. B. G. M. Verheij
openaire   +3 more sources

The Mendelian compromise

Land Use Policy, 1995
Abstract Many polarized land use conflicts, especially with respect to the development of natural ecosystems for industrial activity such as commercial forestry, are in need of equitable and flexible solutions. Assuming that major interests can be grouped into two competing proponent groups, that alternative land uses are equally appropriate and that
openaire   +2 more sources

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