Results 181 to 190 of about 319,715 (326)

Mendelian randomization: Principles and methods [PDF]

open access: yesNetwork Biology
Mendelian randomization (MR) is a methodology for evaluating causality in observational studies. MR tries to find the fact that genotypes are not susceptible to reverse causation and confounding based on Mendel's law of inheritance.
WenJun Zhang
doaj  

Revealing the profile of undergraduate students’ understanding of mendelian inheritance concepts [PDF]

open access: bronze
Hidayati Maghfiroh   +7 more
openalex   +1 more source

Genomic Analysis of Inbreeding Depression on Productive Traits in Rubia Galega Beef Cattle Breed

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In autochthonous livestock breeds with small populations, such as the Rubia Galega from Galicia (Spain), mating between relatives is common and can lead to inbreeding depression. Genomic inbreeding coefficients were estimated for 4984 animals using ~63,000 SNPs to assess inbreeding depression in four key traits: age at first calving (AFC) with
N. Mejuto‐Vázquez   +6 more
wiley   +1 more source

Ontogeny of escape response and body shape in threespine stickleback (Gasterosteus aculeatus L.)

open access: yesJournal of Fish Biology, EarlyView.
Abstract Escape responses in fishes provide insight into accelerative motions and behavioural response times of these animals, linking numerous fitness‐related traits. We sought to connect escape response performance to genotype and phenotype across ontogenetic stages within a single population of threespine stickleback (Gasterosteus aculeatus L.) to ...
Aspen M. Kozak   +4 more
wiley   +1 more source

A nickase Cas9 gene-drive system promotes super-Mendelian inheritance in Drosophila [PDF]

open access: gold, 2021
Víctor López Del Amo   +2 more
openalex   +1 more source

Coupling of both a transactivation module and a double‐stranded DNA‐binding domain boosts Cas12i3 variant‐based cytosine and adenine editing in plants

open access: yesJournal of Integrative Plant Biology, EarlyView.
Fusions of a transactivation module and a double‐stranded DNA‐binding domain produced effective Cas12i3 variant‐based cytosine and adenine base editors, with improved C‐to‐T and A‐to‐G base editing efficiency and expanded editing window. Generated herbicide‐resistant rice germplasm by using these base editors demonstrates their potential for precise ...
Chen Zhang   +7 more
wiley   +1 more source

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