Online Mendelian Inheritance in Animals (OMIA): a record of advances in animal genetics, freely available on the Internet for 25 years [PDF]
Animal Genetics, 2020 For the last 25 years, Online Mendelian Inheritance in Animals (OMIA) has been providing free global access to an ever-increasing record of discoveries made by animal geneticists around the world.
F. W. Nicholas
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Super-Mendelian inheritance mediated by CRISPR-Cas9 in the female mouse germline. [PDF]
Nature, 2019 A gene drive biases the transmission of one of the two copies of a gene such that it is inherited more frequently than by random segregation. Highly efficient gene drive systems have recently been developed in insects, which leverage the sequence ...
Grunwald HA +5 more
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Induced mutations for studying Mendelian inheritance
Journal für Kulturpflanzen, 2022 All genetic variation results from mutations. Orders of magnitude can increase mutation rates by applying irradiation or chemical treatment. Genome editing offers new perspectives for mutation induction because mutation sites can be precisely targeted ...
Christian Jung
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Efficient allelic-drive in Drosophila [PDF]
Nature Communications, 2019 Gene-drives use CRISPR-Cas9 to be transmitted in a super-Mendelian fashion. Here the authors develop an allelic-drive for selective inheritance of a desired allele.
Annabel Guichard +9 more
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Perspectives on the Genomics of HSP Beyond Mendelian Inheritance. [PDF]
Front Neurol, 2018 Hereditary Spastic Paraplegia is an extraordinarily heterogeneous disease caused by over 50 Mendelian genes. Recent applications of next-generation sequencing, large scale data analysis, and data sharing/matchmaking, have discovered a quickly expanding ...
Bis-Brewer DM, Züchner S.
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Online Mendelian Inheritance In Man (OMIM) [PDF]
Human Mutation, 2000 Online Mendelian Inheritance In Man (OMIM) is a public database of bibliographic information about human genes and genetic disorders. Begun by Dr.
Ada Hamosh +4 more
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Monogenic Autoinflammatory Diseases with Mendelian Inheritance: Genes, Mutations, and Genotype/Phenotype Correlations. [PDF]
Front Immunol, 2017 Autoinflammatory diseases (AIDs) are a genetically heterogeneous group of diseases caused by mutations of genes encoding proteins, which play a pivotal role in the regulation of the inflammatory response.
Martorana D +4 more
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Definitions, 2019 Mendelian inheritance refers to patterns of inheritance that are characteristic of organisms that reproduce sexually. T he Austrian monk Gregor Mendel performed thousands of crosses with garden peas at his monastery during the middle of the 19th century.
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Mendelian inheritance of introrse orientated anthers in Brassica rapa [PDF]
Czech Journal of Genetics and Plant Breeding, 2022 The inheritance of anther orientation of 154 individuals from two B1 populations of Brassica rapa (syn. Brassica campestris) was evaluated under controlled conditions in a greenhouse.
Jaroslav Salava, Derek Lydiate
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Mendelian inheritance of trimodal CpG methylation sites suggests distal cis-acting genetic effects. [PDF]
Clin Epigenetics, 2016 Environmentally influenced phenotypes, such as obesity and insulin resistance, can be transmitted over multiple generations. Epigenetic modifications, such as methylation of DNA cytosine-guanine (CpG) pairs, may be carriers of inherited information.
Zaghlool SB +7 more
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