Results 61 to 70 of about 96,085 (345)

Mendelian Inheritance Pattern and High Mutation Rates of Microsatellite Alleles in the Diatom Pseudo-nitzchia multistriata [PDF]

, 2012
The diatom Pseudo-nitzschia multistriata exhibits a diplontic life cycle composed of an extensive phase of vegetative cell division and a brief phase of sexual reproduction.
Amos, Bengtsson, Brinkmann, Callen, Casteleyn, Chepurnov, Chepurnov, Christophe Legrand, Cloutier, Cock van Oosterhout, De Meester, Dobrowolski, Douhovnikoff, Duret, D’Alelio, D’Alelio, D’Alelio, Ellegren, Ellegren, Ellegren, Evans, Gabriele Procaccini, Guillard, Halkett, Hohoff, Härnström, Kruglyak, Lakeman, Li, Marina Montresor, Ouborg, O’Connell, Reece, Reusch, Round, Rynearson, Rynearson, Rynearson, Schurko, Selkoe, Seyfert, Spurgin, Sylvie V.M. Tesson, Tesson, Valière, van Oosterhout, van Oosterhout, Vanoverbeke, White, Wiebe H.C.F. Kooistra, Zar   +50 more
core   +1 more source

Germline selection of PTPN11 (HGNC:9644) variants make a major contribution to both Noonan syndrome's high birth rate and the transmission of sporadic cancer variants resulting in fetal abnormality

Human Mutation, Volume 43, Issue 12, Page 2205-2221, December 2022., 2022
Mutation frequency heat map of spontaneous PTPN11 variants show spatial clustering in the testis due to germline selection explaining the high birth incidence of Noonan syndrome. Some somatic PTPN11 cancer mutations are similarly clustered in testis. Abstract Some spontaneous germline gain‐of‐function mutations promote spermatogonial stem cell clonal ...
Jordan Eboreime, Soo‐Kyung Choi, Song‐Ro Yoon, Anastasiia Sadybekov, Vsevolod Katritch, Peter Calabrese, Norman Arnheim   +6 more
wiley   +1 more source

An Overview of Canine Inherited Neurological Disorders with Known Causal Variants

Animals, 2023
Hereditary neurological conditions documented in dogs encompass congenital, neonatal, and late-onset disorders, along with both progressive and non-progressive forms.
Vlad Cocostîrc, Anamaria Ioana Paștiu, Dana Liana Pusta   +2 more
doaj   +1 more source

VariantAlert: A web‐based tool to notify updates in genetic variant annotations

Human Mutation, Volume 43, Issue 12, Page 1808-1815, December 2022., 2022
Abstract The reinterpretation of variants based on updated annotations is part of the routine work of research laboratories: the more data is collected about a specific variant, the higher the probability to reinterpret its classification. To support this task, we developed VariantAlert, a web‐based tool to help researchers and clinicians to be ...
Rossano Atzeni, Matteo Massidda, Giorgio Fotia, Paolo Uva   +3 more
wiley   +1 more source

Single nucleotide polymorphisms for parentage testing of horse breeds in Korea [PDF]

Animal Bioscience
Objective In this study, we aimed to evaluate the usability single nucleotide polymorphisms (SNPs) for parentage testing of horse breeds in Korea. Methods The genotypes of 93 horse samples (38 Thoroughbred horses, 17 Jeju horses, 20 Quarter horses, and ...
Sun-Young Lee, Su-Min Kim, Baatartsogt Oyungerel, Gil-Jae Cho   +3 more
doaj   +1 more source

Mendelian inheritance of sex [PDF]

Archiv für Entwicklungsmechanik der Organismen, 1909
n ...
openaire   +2 more sources

The next 10 years of behavioural genomic research

JCPP Advances, Volume 2, Issue 4, December 2022., 2022
Three transformative developments for behavioural genomic research in the next 10 years are described. First, behavioural genomic research will use dimensional measures to reveal the hierarchical genetic architecture of psychopathology. A second direction for behavioural genomic research will be to investigate causa models of GE interplay.
Robert Plomin
wiley   +1 more source

DETECTION OF MENDELIAN AND GENOTYPE FREQUENCY OF GROWTH HORMONE GENE IN ONGOLE CROSSBRED CATTLE MATED BY THE ARTIFICIAL INSEMINATION TECHNIQUE

Journal of the Indonesian Tropical Animal Agriculture, 2014
The objectives of this study were to detect the Mendelian mode inheritance of growth hormone(GH) and to establish genotype frequency of GH gene in Ongole-crossbred cattle mated by the artificialinsemination (AI) technique.
U. Paputungan, L. Hakim, G. Ciptadi, H.F.N. Lapian   +3 more
doaj   +1 more source

Epigenetic regulation by heritable RNA. [PDF]

PLoS Genetics, 2014
Genomic concepts are based on the assumption that phenotypes arise from the expression of genetic variants. However, the presence of non-Mendelian inheritance patterns provides a direct challenge to this view and suggests an important role for ...
Reinhard Liebers, Minoo Rassoulzadegan, Frank Lyko   +2 more
doaj   +1 more source

Nuclear mutations affecting mitochondrial structure and function in Chlamydomonas [PDF]

, 1977
Wild type cells of the green alga Chlamydomonas reinhardtii can grow in the in the dark by taking up and respiring exogenously supplied acetate. Obligate photoautotrophic (dark dier, dk) mutants of this alga have been selected which grow at near wild ...
Boynton, J. E., Gillham, N. W., Wiseman, Andrew   +2 more
core   +1 more source