Results 71 to 80 of about 319,715 (326)

Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis [PDF]

, 2005
The genetic system on Trypanosoma brucei has been analysed by generating large numbers of independent progeny clones from two crosses, one between two cloned isolates of Trypanosoma brucei brucei and one between cloned isolates of T. b.
Annette MacLeod, Alison Tweedie, Sarah McLellan, Sonya Taylor, Anneli Cooper, Lindsay Sweeney, C. Michael R. Turner, Andy Tait, Hoare, Gibson, Tibayrenc, MacLeod, MacLeod, MacLeod, Gibson, Turner, Jenni, Sternberg, Gibson, Tait, Gibson, Le Page, Paindovoine, Hope, Su, Su, Martinelli, Culleton, Martinelli, Su, Shirley, Tait, MacLeod, El-Sayed, Hall, Benson, Gaunt, Tait, Gibson, Schweizer, Gibson, Gibson, Hassold, Hide, Van Den Abbeele   +44 more
core   +1 more source

Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease

Scientific Reports, 2021
Inflammatory bowel disease (IBD), clinically defined as Crohn’s disease (CD), ulcerative colitis (UC), or IBD-unclassified, results in chronic inflammation of the gastrointestinal tract in genetically susceptible hosts.
Julie E. Horowitz, Neil Warner, Jeffrey Staples, Eileen Crowley, Nehal Gosalia, Ryan Murchie, Cristopher Van Hout, Karoline Fiedler, Gabriel Welch, Alejandra Klauer King, Jeffrey G. Reid, John D. Overton, Aris Baras, Alan R. Shuldiner, Anne Griffiths, Omri Gottesman, Aleixo M. Muise, Claudia Gonzaga-Jauregui   +17 more
doaj   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Complex segregation analysis of pedigrees from the Gilda Radner Familial Ovarian Cancer Registry reveals evidence for mendelian dominant inheritance. [PDF]

PLoS ONE, 2009
BACKGROUND:Familial component is estimated to account for about 10% of ovarian cancer. However, the mode of inheritance of ovarian cancer remains poorly understood.
Bamidele O Tayo, Richard A DiCioccio, Yulan Liang, Maurizio Trevisan, Richard S Cooper, Shashikant Lele, Lara Sucheston, Steven M Piver, Kunle Odunsi   +8 more
doaj   +1 more source

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, EarlyView.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source

Nance‐Horan Syndrome: Further Delineation of the Affected Male and the Female Carrier Phenotypes

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nance‐Horan syndrome (NHS; OMIM 302350) is a rare, X‐linked syndrome characterized by bilateral congenital cataracts leading to profound vision loss, specific dental anomalies including characteristic screwdriver blade‐shaped incisors, facial anomalies, and intellectual disability.
Maria K. Haanpää, Chad R. Haldeman‐Englert, Marja Hietala, Melisa S. Tanverdi, Patrick P. Koty, Diana Brightman, Eniolami Dosunmu, Shailja Tibrewal, Savleen Kaur, Anupriya Kaur, Raj Kumar Verma, Alejandra G. de Alba Campomanes, Virginia Utz, Anne M. Slavotinek, Cynthia Curry   +14 more
wiley   +1 more source

DETECTION OF MENDELIAN AND GENOTYPE FREQUENCY OF GROWTH HORMONE GENE IN ONGOLE CROSSBRED CATTLE MATED BY THE ARTIFICIAL INSEMINATION TECHNIQUE [PDF]

Journal of the Indonesian Tropical Animal Agriculture, 2012
The objectives of this study were to detect the Mendelian mode inheritance of growth hormone (GH) and to establish genotype frequency of GH gene in Ongole-crossbred cattle mated by the artificial insemination (AI) technique.
U. Paputungan, L. Hakim, G. Ciptadi, H.F.N. Lapian   +3 more
doaj  

Ernst Rüdin's Unpublished 1922-1925 Study "Inheritance of Manic-Depressive Insanity": Genetic Research Findings Subordinated to Eugenic Ideology.

PLoS Genetics, 2015
In the early 20th century, there were few therapeutic options for mental illness and asylum numbers were rising. This pessimistic outlook favoured the rise of the eugenics movement.
Gundula Kösters, Holger Steinberg, Kenneth Clifford Kirkby, Hubertus Himmerich   +3 more
doaj   +1 more source

Evolutionary Multiplayer Games

, 2014
Evolutionary game theory has become one of the most diverse and far reaching theories in biology. Applications of this theory range from cell dynamics to social evolution.
Gokhale, Chaitanya S., Traulsen, Arne
core   +1 more source

Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36 [PDF]

, 2001
Kufor-Rakeb syndrome is an autosomal recessive nigro-striatal-pallidal-pyramidal neurodegeneration. The onset is in the teenage years with clinical features of Parkinson’s disease plus spasticity, supranuclear upgaze paresis, and dementia.
Al-Din, A., Bond, J., Crow, Y., Hampshire, D.J., Mubaidin, A., Roberts, E., Woods, C.G., Wriekat, A.L.   +7 more
core   +2 more sources