Results 251 to 260 of about 4,310,301 (302)

Inflammation in atherosclerotic cardiovascular disease: From diagnosis to treatment

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Inflammation in atherosclerotic cardiovascular disease. Residual inflammatory risk (RIR), defined by high‐sensitive C‐reactive protein (hsCRP) concentration of ≥2 mg/L, represents a strong predictor of future atherosclerotic cardiovascular disease (ASCVD) events. Although increased hsCRP values ≥2 mg/L might be detected in every three out of five ASCVD
Natalie Arnold, Wolfgang Koenig
wiley   +1 more source

Phenotypic heterogeneity in familial epilepsies is influenced by polygenic risk for generalized and focal epilepsies

open access: yesEpilepsia, EarlyView.
Abstract Objective Although previous research shows that generalized and focal epilepsies have at least some distinct genetic influences, it remains uncertain why some families manifest both types of epilepsy. We tested two hypotheses: (1) families with both generalized and focal epilepsy carry separate risk alleles for both types; and (2) within mixed
Colin A. Ellis   +5 more
wiley   +1 more source

Association of diabetic nephropathy with lipid metabolism: a Mendelian randomization study. [PDF]

open access: yesDiabetol Metab Syndr
Xie P   +10 more
europepmc   +1 more source

Mendelian Randomization as an Approach to Assess Causality Using Observational Data

open access: bronze, 2016
Peggy Sekula   +3 more
openalex   +1 more source

Clinical whole genome sequencing in pediatric epilepsy: Genetic and phenotypic spectrum of 733 individuals

open access: yesEpilepsia, EarlyView.
Abstract Objective A large proportion of pediatric epilepsies have an underlying genetic etiology. Limited studies have explored the efficacy of whole genome sequencing (WGS) in a clinical setting. Our academic–clinical center implemented clinical whole exome sequencing (WES) in 2014, then transitioned to WGS from 2015.
Olivia J. Henry   +10 more
wiley   +1 more source

Obesity and Multiple Sclerosis: A Mendelian Randomization Study

open access: gold, 2016
Lauren E. Mokry   +5 more
openalex   +2 more sources

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