Results 271 to 280 of about 95,337 (328)

Natural variations in MdBPM2/MdRGLG3‐MdNAC83 network controlling the quantitative segregation of apple fruit storability

open access: yesJournal of Integrative Plant Biology, EarlyView.
During postharvest cold storage of apples, the NAC transcription factor MdNAC83 binds to the promoters and activates the expression of downstream genes and is regulated by E3 ligases, which promote its ubiquitination and degradation. Genetic variants in MdNAC83 and its downstream genes form a network to regulate apple fruit storability.
Bei Wu   +7 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah   +8 more
wiley   +1 more source

A Principled Framework for Mendelian Randomization in Oral Health Research

open access: yesJournal of Periodontal Research, EarlyView.
This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir   +5 more
wiley   +1 more source

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