Results 31 to 40 of about 4,846,999 (189)

Serum/glucocorticoid-inducible kinase 1 deficiency induces NLRP3 inflammasome activation and autoinflammation of macrophages in a murine endolymphatic hydrops model

open access: yesNature Communications, 2023
The immune response has been suggested to be involved in the pathology of Ménière’s disease. Here the authors implicate serum glucocorticoid-inducible kinase 1 as a regulator of the NLRP3 inflammasome and link to macrophage function in a model of Ménière’
Dao-Gong Zhang   +10 more
doaj   +1 more source

Contrast-enhanced magnetic resonance imaging in the diagnosis of Meniere’s disease: vague future or tangible reality?

open access: yesAlʹmanah Kliničeskoj Mediciny, 2021
Meniere's disease is characterized by vertigo, inconsistent hearing loss and progressive deterioration of audiological and vestibular functions. The attacks of Meniere's disease occur without obvious triggers and disrupt social adaptation of patients ...
E. A. Stepanova
doaj   +1 more source

Relationship Between the Onset of Ménière's Disease and Sympathetic Hyperactivity

open access: yesFrontiers in Neurology, 2022
ObjectiveThe pathogenesis of Ménière's disease is still largely unknown; however, it is known to be strongly associated with stress. Excessive stress can cause hyperactivity of the sympathetic autonomic nervous system.
Masanori Ishii   +6 more
doaj   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Assessment of Vestibulo-Masseteric Reflex Pathway in Individuals with Definite Meniere’s Disease

open access: yesJournal of Indian Speech Language & Hearing Association
Introduction: Vestibulo-masseteric reflex pathway was assessed in individuals with definite Meniere’s disease using masseter vestibular-evoked myogenic potential (mVEMP).
R. Kalaiyarasan, Sujeet Kumar Sinha
doaj   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

open access: yesChemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi   +6 more
wiley   +1 more source

A multicenter, controlled, randomized trial of home‐applied dual‐light photodynamic therapy in stage I to III periodontitis (LumoNorth2022 study)

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg   +9 more
wiley   +1 more source

Surgery for Meniere's disease

open access: yes, 2013
Background This is an update of a Cochrane review first published in The Cochrane Library in Issue 1, 2010. Meniere's disease is characterised by three major symptoms: vertigo, deafness, and tinnitus or aural fullness, all of which are discontinuous and ...
Verschuur, HP   +2 more
core   +1 more source

The Relationship Between Fatigue, Sleep, Dietary Consumption, and Meniere's Disease

open access: yes, 2021
Analysis of patient-reported measures of fatigue, sleep, and dietary consumption in those with Meniere's Disease to determine if any relationships exist between these factors and the frequency and severity of acute attacks of Meniere's ...
Jess Tyrrell   +5 more
core   +1 more source

Intervention Outcomes for Meniere's Disease: An Umbrella Review

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective To assess and summarize the outcomes of major pharmacologic, device‐based, and surgical interventions reported in systematic reviews and meta‐analyses for the treatment of Meniere's disease. Data Sources CINAHL, Cochrane, PubMed, Scopus.
Warren B. Chun   +7 more
wiley   +1 more source

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