Results 41 to 50 of about 5,675 (171)

Serum/glucocorticoid-inducible kinase 1 deficiency induces NLRP3 inflammasome activation and autoinflammation of macrophages in a murine endolymphatic hydrops model

open access: yesNature Communications, 2023
The immune response has been suggested to be involved in the pathology of Ménière’s disease. Here the authors implicate serum glucocorticoid-inducible kinase 1 as a regulator of the NLRP3 inflammasome and link to macrophage function in a model of Ménière’
Dao-Gong Zhang   +10 more
doaj   +1 more source

Relationship Between the Onset of Ménière's Disease and Sympathetic Hyperactivity

open access: yesFrontiers in Neurology, 2022
ObjectiveThe pathogenesis of Ménière's disease is still largely unknown; however, it is known to be strongly associated with stress. Excessive stress can cause hyperactivity of the sympathetic autonomic nervous system.
Masanori Ishii   +6 more
doaj   +1 more source

Contrast-enhanced magnetic resonance imaging in the diagnosis of Meniere’s disease: vague future or tangible reality?

open access: yesAlʹmanah Kliničeskoj Mediciny, 2021
Meniere's disease is characterized by vertigo, inconsistent hearing loss and progressive deterioration of audiological and vestibular functions. The attacks of Meniere's disease occur without obvious triggers and disrupt social adaptation of patients ...
E. A. Stepanova
doaj   +1 more source

Nanoporous Silica Embedded in Nanoporous Platinum: A Versatile Composite Coating for Implant‐Associated Drug Delivery From Neuronal Electrodes

open access: yesAdvanced Materials Technologies, EarlyView.
Nanoporous silica nanoparticles incorporated in nanoporous platinum offer the possibility for implant‐associated drug delivery from neuronal electrodes. ABSTRACT Sensorineural hearing loss, resulting from damage to the hair cells of the inner ear, profoundly impairs quality of life.
Mosaieb Habib   +10 more
wiley   +1 more source

Experience of immunological aspects of Meniere’s Disease [PDF]

open access: yes, 2015
Experience of immunological aspects of Meniere’s ...
MATTEUCCI, JACOPO   +4 more
core  

Immunohistochemical localization and mRNA expression of aquaporins in the macula utriculi of patients with Meniere’s disease and acoustic neuroma [PDF]

open access: yes, 2010
Meniere’s disease is nearly invariably associated with endolymphatic hydrops (the net accumulation of water in the inner ear endolymphatic space). Vestibular maculae utriculi were acquired from patients undergoing surgery for Meniere’s disease and ...
Lopez, Ivan A.   +7 more
core   +1 more source

A systematic review on the contribution of DNA methylation to hearing loss

open access: yesClinical Epigenetics
Background DNA methylation may have a regulatory role in monogenic sensorineural hearing loss and complex, polygenic phenotypic forms of hearing loss, including age-related hearing impairment or Meniere disease.
Vibha Patil   +2 more
doaj   +1 more source

An Imaging‐Guided, Patient‐Specific Guiding Aid (RWNGuide) for Safe and Reproducible Inner Ear Drug Delivery

open access: yesAdvanced Materials Technologies, EarlyView.
A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo   +4 more
wiley   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

open access: yesAdvanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen   +11 more
wiley   +1 more source

Audio-vestibular and radiological analysis in Meniere’s disease [PDF]

open access: yes, 2022
Objective: Intravenous gadolinium-enhanced inner ear magnetic resonance imaging (IV Gd-enhanced inner ear MRI) is a new technique for diagnosing Meniere’s disease (MD).
Hamdı Caklı (14434797)   +5 more
core   +1 more source

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