Results 61 to 70 of about 8,996,662 (262)

Discrete Elastic Inner Vector Spaces with Application in Time Series and Sequence Mining [PDF]

IEEE Transactions on Knowledge and Data Engineering (2012) pp 1-14, 2012
This paper proposes a framework dedicated to the construction of what we call discrete elastic inner product allowing one to embed sets of non-uniformly sampled multivariate time series or sequences of varying lengths into inner product space structures.
arxiv   +1 more source

The effect of noise exposure on the vestibular systems of dental technicians

Noise and Health, 2019
Background: Noise exposure is the primary cause of acquired hearing loss in several occupational settings, including dental laboratories and clinics. However, the impact of noise exposure on the vestibular system is not as well researched.
Safa Alqudah
doaj   +1 more source

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

Advanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang, Li Zhang, Sen Chen, Le Xie, Yue Qiu, Chenyang Kong, Ge Yin, Weijia Kong, Yu Sun   +8 more
wiley   +1 more source

An ultra-rare missense variant in the KIF1B gene linked to autoinflammatory Menière’s disease

npj Genomic Medicine
Menière’s disease (MD) is an inner ear disorder characterised by episodes of vertigo, sensorineural hearing loss and tinnitus linked to autoinflammation and/or type 2 immune response.
Pablo Cruz-Granados, Giselle Bianco-Bortoletto, Ismael Aran, Victoria Rivero de Jesus, Jose A. Lopez-Escamez   +4 more
doaj   +1 more source

Detection and Grading of Endolymphatic Hydrops in Menière Disease Using MR Imaging

American Journal of Neuroradiology, 2014
BACKGROUND AND PURPOSE: Endolymphatic hydrops has been recognized as the underlying pathophysiology of Menière disease. We used 3T MR imaging to detect and grade endolymphatic hydrops in patients with Menière disease and to correlate MR imaging findings ...
K. Baráth, Bernhard Schuknecht, A. Naldi, T. Schrepfer, C. Bockisch, Stefan C. A. Hegemann   +5 more
semanticscholar   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

Advanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa, Jiali Wang, Mengzhao Xun, Jessica M. Rosenholm, Wuqing Wang, Yilai Shu, Hongbo Zhang   +6 more
wiley   +1 more source

Histamine H4 receptor gene polymorphisms: a potential contributor to Meniere disease. [PDF]

BMC Med Genomics, 2019
Background The immune system is likely involved in the pathophysiology of Meniere’s disease (MD). However, its role of patients with MD has not been well studied.
Qin D, Zhang H, Wang J, Hong Z.
europepmc   +2 more sources

Distinct MicroRNA Profiles in the Perilymph and Serum of Patients With Menière's Disease

Frontiers in Neurology, 2021
Hypothesis: Menière's disease microRNA (miRNA) profiles are unique and are reflected in the perilymph and serum of patients.Background: Development of effective biomarkers for Menière's disease are needed. miRNAs are small RNA sequences that downregulate
Matthew Shew, Helena Wichova, Madeleine St. Peter, Athanasia Warnecke, Hinrich Staecker   +4 more
doaj   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

The State of High‐Resolution Imaging of the Human Inner Ear: A Look Into the Black Box

Advanced Science, EarlyView.
High‐resolution imaging of the cochlea is challenged by numerous unique aspects of this organ, where sensorineural cells, crucial for hearing, are too small for conventional modalities like magnetic resonance imaging and computed tomography. This article reviews current imaging techniques, emerging technologies, and innovations aimed at improving ...
Shelley Batts, Nancy Pham, Guillermo Tearney, Konstantina M. Stankovic   +3 more
wiley   +1 more source