Results 71 to 80 of about 103,286 (345)

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Proposed response assessment and endpoints for meningioma clinical trials: report from the Response Assessment in Neuro-Oncology Working Group.

Neuro-Oncology, 2018
No standard criteria exist for assessing response and progression in clinical trials involving patients with meningioma, and there is no consensus on the optimal endpoints for trials currently under way. As a result, there is substantial variation in the
Raymond Y. Huang, W. Bi, M. Weller, T. Kaley, J. Blakeley, I. Dunn, E. Galanis, M. Preusser, Michael M. McDermott, L. Rogers, J. Raizer, D. Schiff, R. Soffietti, J. Tonn, M. Vogelbaum, D. Weber, D. Reardon, P. Wen   +17 more
semanticscholar   +1 more source

A Hybrid Transfer Learning Framework for Brain Tumor Diagnosis

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A novel hybrid transfer learning approach for brain tumor classification achieves 99.47% accuracy using magnetic resonance imaging (MRI) images. By combining image preprocessing, ensemble deep learning, and explainable artificial intelligence (XAI) techniques like gradient‐weighted class activation mapping and SHapley Additive exPlanations (SHAP), the ...
Sadia Islam Tonni, Md. Alif Sheakh, Mst. Sazia Tahosin, Md. Zahid Hasan, Taslima Ferdaus Shuva, Touhid Bhuiyan, Muhammad Ali Abdullah Almoyad, Nabil Anan Orka, Md. Tanvir Rahman, Risala Tasin Khan, M. Shamim Kaiser, Mohammad Ali Moni   +11 more
wiley   +1 more source

Novel insights into meningioma brain invasion with spatial transcriptomic profiling

Acta Neuropathologica Communications
Brain invasion of meningioma is a controversial clinicopathological grading criterion that correlates with prognosis and is a stand-alone criterion for WHO grade 2 meningioma.
Andrea Daniela Maier, Claes Ottzen Laurentiussen, Signe Regner Michaelsen, Lorenzo Perino, Tobias Overlund Stannius, Dylan Scott Lykke Harwood, Marc Nihøj Klausen, Jeppe Haslund-Vinding, Nicolai Schou Bager, David Scheie, Ane Yde Schmidt, Linea Cecilie Melchior, Aušrinė Areškevičiūtė, Frederik Vilhardt, Knud Elnegaard Josefsen, David R. Raleigh, Frederik Otzen Bagger, Tiit Mathiesen, Bjarne Winther Kristensen   +18 more
doaj   +1 more source

Multiple meningiomas consisting of fibrous meningioma, transitional meningioma, and meningotheliomatous meningioma in one adult patient

Asian Journal of Neurosurgery, 2015
Multiple histopathology of meningioma is a condition in which the patient has more than one histopathology feature of meningioma in different intracranial locations, with or without sign of neurofibromatosis. Meningiomas are the most common, non-glial, primitive intracranial tumors; their prevalence among operated tumors is around 13-19%.
Yudoyono, Farid, Sidabutar, Roland, Arifin, Muhammad Zafrullah, Faried, Ahmad   +3 more
openaire   +3 more sources

Integrated models incorporating radiologic and radiomic features predict meningioma grade, local failure, and overall survival

Neuro-Oncology Advances, 2019
Background We investigated prognostic models based on clinical, radiologic, and radiomic feature to preoperatively identify meningiomas at risk for poor outcomes.
O. Morin, William C. Chen, F. Nassiri, M. Susko, S. Magill, H. Vasudevan, A. Wu, M. Vallières, E. Gennatas, G. Valdes, M. Pekmezci, P. Alcaide-Leon, A. Choudhury, Y. Interian, S. Mortezavi, Kerem Turgutlu, N. Bush, T. Solberg, S. Braunstein, P. Sneed, A. Perry, G. Zadeh, M. McDermott, J. Villanueva-Meyer, D. Raleigh   +24 more
semanticscholar   +1 more source

Lost and Found: Is Olfactory Recovery More Promising After COVID‐19 Than Other Causes, Even 2 Years Later?

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is a hallmark feature of COVID‐19, yet the potential for recovery with long‐standing COVID‐19‐related smell loss (CRSL) remains uncertain, particularly when treatment is initiated years later. This study evaluated olfactory outcomes in patients with CRSL compared with non‐COVID‐19‐related smell loss (non‐CRSL),
John W. Hunsicker, Mabel Berg, Nicolaus Knight, Jessica W. Grayson, Bradford A. Woodworth, Justin H. Turner, Do‐Yeon Cho   +6 more
wiley   +1 more source

Intraosseous metaplastic meningioma: A case report

Radiology Case Reports, 2021
Metaplastic meningioma is a rare World Health Organization Grade I meningioma subtype, accounting for 0.2%-1.6% of all meningiomas. Primary extradural meningiomas represent less than 2% of all meningiomas, with intraosseous meningioma as a subtype of ...
Yusuke Utsunomiya, MD, Nobuyuki Mori, MD, PhD, Yuya Matsui, MD, Hiroki Katsushima, MD, PhD, Kenji Hashimoto, MD, PhD, Akihiro Furuta, MD, PhD   +5 more
doaj   +1 more source

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community

Annals of Neurology, EarlyView.
Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta, Davide Liborio Vetrano, Erika J. Laukka, Grégoria Kalpouzos, Javier Oltra, Debora Rizzuto, Marco Canevelli, Claudia Fredolini, Chengxuan Qiu, Bengt Winblad, Laura Fratiglioni, Giulia Grande   +11 more
wiley   +1 more source

Is DNA Methylation a Ray of Sunshine in Predicting Meningioma Prognosis?

Frontiers in Oncology, 2020
Meningioma is the most common intracranial tumor, and recent studies have drawn attention to the importance of further research on malignant meningioma.
Lu Shen, Danfeng Lin, Lu Cheng, Sheng Tu, Haijian Wu, Weilin Xu, Yuanbo Pan, Xiaochen Wang, Xiaochen Wang, Jianmin Zhang, Jianmin Zhang, Jianmin Zhang, Anwen Shao   +12 more
doaj   +1 more source