Clinical trials show similar safety outcomes including febrile convulsion rates for GSK’s and Merck’s measles-mumps-rubella (MMR) vaccines [PDF]
Combined measles-mumps-rubella (MMR) vaccines produced by GSK (GSK-MMR) and Merck (Merck-MMR) have demonstrated effectiveness and an acceptable safety profile, as documented over decades of post-licensure use in various regions worldwide.
Md Ahsan Habib +4 more
doaj +2 more sources
Subsets of cerebrospinal fluid lymphocytes in acute pediatric respiratory viral infection with meningeal syndrome [PDF]
Current urgency of studying the intrathecal cellular immune response to infections of central nervous system is determined by limited knowledge on existing data about mechanisms of the brain immune protection in normal and diseased state.
A. A. Zhirkov +4 more
doaj +3 more sources
First Case of West Nile Fever in a Child in Autonomous Republic of Crimea [PDF]
The article shows a case report of West Nile fever in 11-year-old boy taken from own clinical experience. The duration of the diseases was typical, with fever, meningism, lymphadenitis, hyperemic of facial and chest skin, conjunctivitis, pain in muscles ...
N.V. Rymarenko +3 more
doaj +2 more sources
Disseminated cryptococcosis in a HIV-negative patient: Case report of a newly diagnosed hypertensive adult presenting with hemiparesis [PDF]
We report a case of disseminated cryptococcosis in a 42-year old immunocompetent female. Prior to admission at Bugando Medical Center, the patient was attended at three hospitals for hypertension and clinically diagnosed malaria.
Raymond M. Wilson +9 more
doaj +2 more sources
Bilateral sensorineural hearing loss secondary to sympathetic ophthalmia in a human leukocyte antigen-A2 positive patient [PDF]
We report a case of sympathetic ophthalmia 1 month following trauma in a 71-year-old immunocompetent female patient of Indian origin. The patient was hospitalized with signs and symptoms of meningism, ataxia, and neurosensory deafness.
Konstantinos T Tsaousis +2 more
doaj +2 more sources
Learning From a Missed Diagnosis: Complete Agenesis of the Corpus Callosum With Benign Hydrocephalus. [PDF]
ABSTRACT In agenesis of the corpus callosum, ventriculomegaly without evidence of cerebrospinal fluid obstruction often requires no surgical intervention. Regular follow‐up every 3–6 months, then annually, is essential to monitor for signs of raised intracranial pressure or neurological decline—prompting advanced imaging and consideration of surgical ...
Samaranayake JE +6 more
europepmc +2 more sources
2024 European guidelines for the management of genital herpes [PDF]
Genital herpes—guidelines for diagnostic and treatment (2024): strategies for diagnosis, management and follow‐up of the most common sexually transmitted infection. The guidelines covers common clinical scenarios (including recurrent genital herpes), infection during pregnancy and coinfection with human immunodeficiency virus.
Rajul Patel +10 more
wiley +5 more sources
Severe Headache and Acute Blindness: A Case of Pituitary Apoplexy. [PDF]
ABSTRACT Pituitary apoplexy is a rare, life‐threatening syndrome that commonly occurs in the adenomatous pituitary gland. It presents with a myriad of severe neuroendocrine and ophthalmological signs and symptoms. Early diagnosis and prompt treatment are vital in the management of pituitary apoplexy.
Faiza AR +4 more
europepmc +2 more sources
Positive real-time PCR in pneumococcal meningitis 12 hours after initiation of antibiotic therapy – case report [PDF]
Background Purulent meningitis poses a significant clinical challenge with high mortality. We present the case of a 54-year-old female transferred to our emergency department with suspected bacterial meningitis, later diagnosed as an Austrian syndrome ...
Cem Thunstedt +5 more
doaj +2 more sources
A cohort study to assess the new WHO Japanese encephalitis surveillance standards [PDF]
OBJECTIVE: To assess the field-test version of the new WHO Japanese encephalitis (JE) surveillance standards. METHODS: We applied the clinical case definition of acute encephalitis syndrome (AES), laboratory diagnostic criteria and case classifications ...
Tom Solomon +6 more
doaj +3 more sources

