Results 91 to 100 of about 29,060 (214)
Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li +7 more
wiley +1 more source
Deficiency of immunity to poliovirus type 3: a lurking danger? [PDF]
Background: Europe was certified to be polio-free in 2002 by the WHO. However, wild polioviruses remain endemic in India, Pakistan, Afghanistan, and Nigeria, occasionally causing polio outbreaks, as in Tajikistan in 2010.
Doerr, Hans W. +3 more
core +2 more sources
ABSTRACT Dermoid cysts are congenital inclusion lesions that arise from ectodermal entrapment along embryonic fusion lines; occipital extracranial involvement is particularly uncommon. Cardiofaciocutaneous syndrome type 4 (CFC4), a RASopathy caused by pathogenic variants in MAP2K2, presents with characteristic dermatologic, craniofacial, and ...
Mona Alkallabi +4 more
wiley +1 more source
Neurological complications of immune checkpoint inhibitors: what happens when you \u27take the brakes off\u27 the immune system. [PDF]
Patients with advanced malignancies treated with immune checkpoint inhibitors are at increased risk for developing immune-related neurological complications.
Dalakas, Marinos
core +1 more source
A Report on the Diagnosis and Treatment of Multiple Fungal Critical Brain Abscesses A Case Report
ABSTRACT Multiple Candida glabrata (C. glabrata) brain abscesses are an exceptionally rare central‐nervous‐system infection. Clinical data on diagnosing and managing multiple Candida glabrata brain abscesses are still scarce. Here we reported a 66‐year‐old patient with multiple C. glabrata brain abscesses confirmed by cerebrospinal‐fluid puncture.
Chongyin Zhang +4 more
wiley +1 more source
The aetiology of chronic aseptic meningitis is difficult to establish. Candida meningitis in particular is often diagnosed late, as cerebrospinal fluid (CSF) work-up and imaging findings are nonspecific.
Andrea B. Kuenzli +9 more
doaj +1 more source
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee +14 more
wiley +1 more source
MOLECULAR-EPIDEMIOLOGICAL INVESTIGATION OF THE OUTBREAK OF ASEPTIC MENINGITIS IN NOVOSIBIRSK REGION
The aim of this study was to investigate the outbreak of aseptic meningitis in theNovosibirskregion in 2008–2009. We studied genetic diversity and molecular-epidemiological characteristics of human enteroviruses that caused aseptic meningitis.
A. V. Demina +3 more
doaj +1 more source
ABSTRACT Over the years, numerous D‐ and z‐values have been published in the scientific literature. While these values initially appear to be valid criteria for assessing and comparing the heat resistance of different microorganisms under the same conditions or the same microorganism under different conditions, this is not always the case.
Astrid Gędas, Agnes Weiss
wiley +1 more source

