Results 181 to 190 of about 1,352,938 (323)

A Rare Clinical Manifestation of Disseminated Tuberculosis: Case Report of Tuberculous Meningitis With Flaccid Paralysis

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case highlights a rare presentation of disseminated tuberculosis in a child, manifesting as tuberculous meningitis and flaccid paralysis due to spinal tuberculosis. Timely initiation of antitubercular therapy, corticosteroids, and ventriculoperitoneal shunt placement led to full recovery, emphasizing tuberculosis consideration in atypical
Aisha Haleem   +5 more
wiley   +1 more source

A Report on the Diagnosis and Treatment of Multiple Fungal Critical Brain Abscesses A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Multiple Candida glabrata (C. glabrata) brain abscesses are an exceptionally rare central‐nervous‐system infection. Clinical data on diagnosing and managing multiple Candida glabrata brain abscesses are still scarce. Here we reported a 66‐year‐old patient with multiple C. glabrata brain abscesses confirmed by cerebrospinal‐fluid puncture.
Chongyin Zhang   +4 more
wiley   +1 more source

Predictors of HIV Vertical Transmission in Exposed Infants in Northwest, Ethiopia: A Retrospective Cohort Study

open access: yesHealth Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Although the global plan aimed to eliminate mother‐to‐child transmission of HIV by 2015, an estimated 130,000 children were newly infected, and 84,000 children died from HIV related causes in 2022. In Ethiopia, 3200 children became newly infected and 1,900 children died from HIV related causes in 2022.
Amare Genetu Ejigu   +19 more
wiley   +1 more source

The Role of Macrophages in Cancer: From Basic Research to Clinical Applications

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu   +5 more
wiley   +1 more source

Impact of the COVID‐19 Pandemic on Cochlear Implant Usage in Children

open access: yesOtolaryngology–Head and Neck Surgery, Volume 174, Issue 1, Page 257-264, January 2026.
Abstract Objective To evaluate the impact of the COVID‐19 pandemic on cochlear implant (CI) usage in children by comparing hearing hour percentage (HHP) during the pandemic to prepandemic levels. Study Design Retrospective Cohort Study. Setting Primary Children's Hospital, Utah.
Peter Kfoury   +7 more
wiley   +1 more source

Interaction of Staphylococcus aureus di‐iron Repair of Iron Centers protein with the iron–sulfur cluster assembly SUF system

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract Repair of Iron Centers (RIC) proteins are present in several pathogens, including Staphylococcus aureus, contributing to resistance to nitroxidative stress and virulence. In this work, we investigated the molecular mechanisms by which S. aureus RIC facilitates iron mobilization, through structural analyses and functional studies.
Frederico M. Lourenço   +8 more
wiley   +1 more source

Practice guidelines for the management of bacterial meningitis.

open access: yesClinical Infectious Diseases, 2004
A. Tunkel   +6 more
semanticscholar   +1 more source

Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee   +14 more
wiley   +1 more source

ESCMID guideline: diagnosis and treatment of acute bacterial meningitis.

open access: yesClinical Microbiology and Infection, 2016
D. Beek   +13 more
semanticscholar   +1 more source

A New Class of Benzo[b]Thiophene‐1,3,4‐Oxadizole Bearing 1,2,4‐Oxadiazoles as Potent Antimicrobial Targets: Synthesis, Biological Evaluation, Docking, DFT and ADMET Studies

open access: yesChemistrySelect, Volume 11, Issue 3, 22 January 2026.
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy