Results 111 to 120 of about 19,093 (217)

Fluconazole plus flucytosine versus fluconazole alone for adults with HIV-associated cryptococcal antigenaemia identified through screening: a multi-centre phase III randomised-controlled trial

Trials
Background Despite the expansion of antiretroviral treatment programmes, the incidence and mortality of HIV-associated cryptococcal meningitis remain high in Africa. Cryptococcal antigen (CrAg) in the blood precedes meningitis.
Kyla Murphy, Jeremy S. Nel, Mahomed-Yunus Moosa, Douglas P. Wilson, Merika Tsitsi, Sayoki Mfinanga, Sokoine Kivuyo, Denise Kyazze, Nowshad Alam, Graeme Meintjes, Michelle Eriksson, Jack Adams, Colin Menezes, Ebrahim Variava, John Black, Marise Bremer, Vu Quoc Dat, Thuy Le, Charlotte Schutz, Angela Loyse, Rachel M. Wake, David S. Lawrence, Duolao Wang, Shabbar Jaffar, Joseph N. Jarvis, Thomas S. Harrison, Síle F. Molloy, Nelesh P. Govender   +27 more
doaj   +1 more source

Stealth cryptococcus in an immunocompetent patient

Autopsy and Case Reports
Cryptococcosis occurs primarily in immunocompromised patients. It is difficult to suspect in an immunocompetent patient presenting with a headache.
Emily Ryan, Gia Jackson, Larry Nichols
doaj   +1 more source

Asymptomatic cryptococcal antigenemia is associated with mortality among HIV‐positive patients in Indonesia

Journal of the International AIDS Society, 2014
Introduction Previous studies, mostly from Africa, have shown that serum cryptococcal antigenemia may precede the development of cryptococcal meningitis and early death among patients with advanced HIV infection. We examined cryptococcal antigenemia as a
Ahmad Rizal Ganiem, Agnes Rengga Indrati, Rudi Wisaksana, Hinta Meijerink, Andre van derVen, Bachti Alisjahbana, Reinout vanCrevel   +6 more
doaj   +1 more source

Cryptococcus neoformans and PLWH: the role of serum cryptococcal antigen screening

Journal of Infection in Developing Countries
Introduction: Serum cryptococcal antigen (CrAg) screening is crucial for early diagnosis of cryptococcal meningitis. This study presents the results of CrAg screening among people living with HIV (PLWH) followed in our clinic over the past six years ...
Özlem Gül, Nazife Duygu Demirbaş, Ayşe Barış, Okan Derin, Ceren Atasoy Tahtasakal, Ahsen Öncül, Dilek Yıldız Sevgi, İlyas Dökmetaş   +7 more
doaj   +1 more source

Southern African HIV Clinicians Society guideline for the prevention, diagnosis and management of cryptococcal disease among HIV-infected persons: 2019 update. [PDF]

, 2019
Black, J, Boulware, D, Boyles, T, Chiller, T, Dawood, H, Dlamini, S, Govender, NP, Harrison, TS, Ive, P, Jarvis, J, Karstaedt, A, Madua, MC, Mangena, P, Meintjes, G, Menezes, C, Moosa, M-YS, Motlekar, Z, Nel, J, Potgieter, S, Rabie, H, Reddy, D, Shroufi, A, Stacey, SL, Tsitsi, M, van Cutsem, G, Variava, E, Venter, M, Wake, R, Wilson, D   +28 more
core   +2 more sources

CrAg screening strategy reduces definitive sequelae in people living with HIV

Discover Viruses
Background Screenning cryptococcal antigen (CrAg) of people living with HIV (PLHIV) reduces the morbidity and development of cryptococcal meningitis, but recent publications shows that it does not reduce mortality when comparable with a negative CrAg ...
Marcela de Faria Ferreira, Fabio Brito-Santos, Marcos de Abreu Almeida, Luciana Trilles, Marcia dos Santos Lazera   +4 more
doaj   +1 more source

Cryptococcal meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Cryptococcus neoformans is a kind of encapsulated fungal organism that widely exists in the nature. Because of its neurotropic nature, the central nervous system becomes its major target organ. Cryptococcus neoformans can use "transcellular pathway", "paracellular pathway" and "Trojan horse approach" to cross blood-brain barrier, and then make the ...
Yun-can WANG, Jun⁃ying HE, Hui BU, Yue⁃li ZOU, Wen⁃ting DING   +4 more
openaire   +1 more source

Cerebral infarction related to cryptococcal meningitis in an HIV-infected patient: case report and literature review

Brazilian Journal of Infectious Diseases
Neurological dysfunction as the first manifestation of AIDS has been found in 10 to 20% of symptomatic human immunodeficiency virus infections. However, stroke has rarely been reported in AIDS patients.
Andréa Gurgel Batista Leite, José E. Vidal, Francisco Bonasser Filho, Roberta Schiavon Nogueira, Augusto César Penalva de Oliveira   +4 more
doaj   +1 more source

Treatment of HIV-associated cryptococcal meningitis in South Africa: The case for amphotericin B over conventional dose fluconazole for initial therapy [PDF]

, 2007
Cryptococcal meningitis is a major cause of morbidity and mortality in African AIDS patients, accounting for between 13% and 17% of deaths in Ugandan HIV-infected individuals(1,2) and 44% of deaths in a cohort of HIV-seropositive South African miners.(3)
Bicanic, T, Harrison, TS, Jarvis, JN
core  

Low uptake of antiretroviral therapy after admission with human immunodeficiency virus and tuberculosis in KwaZulu-Natal, South Africa. [PDF]

, 2010
A prospective cohort study was conducted among human immunodeficiency virus (HIV) infected in-patients with tuberculosis (TB) or other opportunistic infections (OIs) in South Africa to estimate subsequent antiretroviral therapy (ART) uptake and ...
Kappagoda, S, Kuritzkes, D R, Maphasa, K T M, Murphy, R A, Smeaton, L, Sunpath, H, Taha, B   +6 more
core   +1 more source