Results 31 to 40 of about 12,406 (149)

Design of B‐Cell Multi‐Epitope Subunit Vaccines Against Glaesserella parasuis by Reverse Vaccinology: An In Silico and In Vivo Study

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Yan Gong   +10 more
wiley   +1 more source

Systematic Review of Postvaccination Ocular Adverse Events: A Comprehensive Analysis of Published Reports

open access: yesJournal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT Ocular adverse events following COVID‐19 vaccination are well described; however, systematic analyses of non‐COVID antiviral vaccines remain limited. This review aimed to evaluate ocular complications associated with non‐COVID antiviral immunizations, including influenza, varicella‐zoster (VZV), human papillomavirus (HPV), and hepatitis B (HBV)
Yaru Zou   +5 more
wiley   +1 more source

Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis

open access: yesFrontiers in Medicine, 2020
Neisseria meningitidis causes sepsis and meningitis in humans. It has been suggested that pathogen genetic variation determines variance in disease severity. Here we report results of a genome-wide association study of 486 N.
Philip H. C. Kremer   +9 more
doaj   +1 more source

Narsoplimab Results in Excellent Survival in Adults and Children With Hematopoietic Cell Transplant Associated Thrombotic Microangiopathy (TA‐TMA)

open access: yesAmerican Journal of Hematology, Volume 100, Issue 11, Page 2040-2051, November 2025.
ABSTRACT Inappropriate complement activation is a key driver of hematopoietic cell transplant‐associated thrombotic microangiopathy (TA‐TMA). Treatment with narsoplimab, an inhibitor of MASP‐2, the effector enzyme of the lectin pathway, resulted in a response rate of 61% in a Phase 2 clinical trial in adults with TA‐TMA.
Michelle L. Schoettler   +6 more
wiley   +1 more source

Successful African introduction of a new Group A meningococcal conjugate vaccine: Future challenges and next steps

open access: yesHuman Vaccines & Immunotherapeutics, 2018
The introduction of a new Group A meningococcal conjugate vaccine, MenAfriVacR, has been a important public health success. Group A meningococcal meningitis has disappeared in all countries where the new Men A conjugate vaccine has been used at public ...
F. Marc LaForce   +3 more
doaj   +1 more source

Meningococcal meningitis C in Tamil Nadu, public health perspectives

open access: yesJournal of Family Medicine and Primary Care, 2014
Meningococcal meningitis has rarely been reported in Tamil Nadu. We report here two children diagnosed with meningococcal meningitis in Vellore, Tamil Nadu, on May 2014. The causative strain was Neisseria meningitidis serotype C.
Kirubah Vasandhi David   +2 more
doaj   +1 more source

The Silent Risk of Sudan Virus: A Review Addressing Global Health Vulnerabilities

open access: yesHealth Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aim Sudan Virus Disease (SVD) is a deadly hemorrhagic fever caused by the Sudan virus, first discovered in Sudan in 1976. This disease has been linked to several outbreaks in sub‐Saharan Africa, particularly in Uganda. The high fatality rate of SVD, ranging from 41% to 70%, emphasizes the critical need for effective preventive ...
Syed Masudur Rahman Dewan   +1 more
wiley   +1 more source

A case of invasive meningococcal disease presenting as myopericarditis

open access: yesClinical Infection in Practice, 2021
Background: Neisseria meningitidis is a universally-feared Gram negative diplococcus, and infection confers high rates of morbidity and mortality despite effective antimicrobial therapy.
Simon M. Durkin   +3 more
doaj   +1 more source

Invasive Meningococcal Disease in a Patient With Complement 7 Deficiency

open access: yesJournal of General and Family Medicine, Volume 26, Issue 6, Page 646-649, November 2025.
ABSTRACT Neisseria meningitidis can cause invasive meningococcal disease (IMD). Individuals with primary complement deficiencies are at a higher risk of developing IMD. However, cases of IMD associated with complement deficiency have rarely been reported in Japan.
Hiroaki Nishioka   +2 more
wiley   +1 more source

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