Results 31 to 40 of about 12,689 (175)

Bacterial Meningitis in Brazil: Baseline Epidemiologic Assessment of the Decade Prior to the Introduction of Pneumococcal and Meningococcal Vaccines.

PLoS ONE, 2013
BackgroundBacterial meningitis is associated with significant burden in Brazil. In 2010, both 10-valent pneumococcal conjugate vaccine and meningococcal capsular group C conjugate vaccine were introduced into the routine vaccination schedule. Haemophilus
Luciano Cesar Pontes Azevedo, Cristiana M Toscano, Ana Luiza Bierrenbach   +2 more
doaj   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Advancing tele‐physiology: A chest patch solution for continuous, non‐invasive remote monitoring in a hypoxic environment

Experimental Physiology, EarlyView.
Abstract Skin‐mounted sensors are thin, flexible and lightweight electronic devices that enable monitoring of multiple physiological parameters. The aim of this study was to provide pilot evidence for possible utilization of a sensorized patch for capturing the bodily response to hypoxia. The subsequent phases of the study comprised a case report and a
Danilo Bondi, Ferdinando Calcagno, Elisa Fioraso, Camillo Di Giulio, Federico Schena, Anna Pedrinolla   +5 more
wiley   +1 more source

Trends in Meningitis Burden and Projections to 2040: A Secondary Analysis of the Global Burden of Disease Study 2023

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Meningitis remains a global health challenge, characterized by substantial regional and etiologic disparities. This study aimed to analyze recent trends, forecast future burden, and examine the influence of development status on meningitis outcomes.
Mehdi Azizmohammad Looha, Ali Saberi Shahrbabaki, Fatemeh Masaebi, Mahmoud Zamani, Farid Zayeri   +4 more
wiley   +1 more source

Seasonal upsurge of pneumococcal meningitis in the Central African Republic [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research, 2019
A high incidence of bacterial meningitis was observed in the Central African Republic (CAR) from December 2015 to May 2017 in three hospitals in the northwest of the country that are within the African meningitis belt.
Thomas Crellen, V. Bhargavi Rao, Turid Piening, Joke Zeydner, M. Ruby Siddiqui   +4 more
doaj   +1 more source

Emergence and Genomic Characterization of a Hypervirulent Klebsiella pneumoniae Isolate From a New Clone in Brazil

Microbiology and Immunology, Volume 70, Issue 5, Page 261-267, May 2026.
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) has emerged globally as a major public health concern, often associated with severe community‐acquired and healthcare‐associated human infections. Despite alerts from PAHO/WHO on convergent hvKp strains with multidrug resistance in Latin America, comprehensive data from Brazil, the region's largest ...
Carlos Henrique Camargo, Ana Beatriz Nascimento Costa, Amanda Yaeko Yamada, Daniel de Sena Miranda, Pedro Smith Pereira Ferraro, Andreia Rodrigues de Souza, Amanda Maria de Jesus Bertani, Karoline Rodrigues Campos, Marlon Benedito Nascimento Santos, Rafaela Mastrangelo Rissetti, Carolina Lechinski de Paula, Patrik Júnior de Lima Paz, Maria Solange Duarte Soares, Christiane Salvador, Giovanna de Pinho Pieri, Jorge Siguemassa Higa, Daniela dos Santos Souza, Márcio Garcia Ribeiro, Claudio Tavares Sacchi, Monique Ribeiro Tiba‐Casas, Geraldine Madalosso, Denise Brandao de Assis   +21 more
wiley   +1 more source

Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez, Javier De la Peña Noya, José Manuel Borrero‐de Acuña   +2 more
wiley   +1 more source

Does clinical exposure to different skin tones during training improve diagnostic ability?

Medical Education, Volume 60, Issue 4, Page 410-417, April 2026.
Abstract Background Previous studies have shown that medical students demonstrate poorer performance when diagnosing pathology in skin of colour (SOC) compared to white skin (WS); it is important to understand the reasons underpinning this. If not addressed, poorer differential diagnostic ability in certain skin tones could entrench existing racial ...
Yusra Shammoon, Anna Coulson, Bethan Trigg, Nariell Morrison, Adam Potts, Moira Pain, Olamide Oguntimehin, Eleanor J. Hothersall‐Davies, Richard Hankins, Celia A. Brown, Amir H. Sam   +10 more
wiley   +1 more source

Successful African introduction of a new Group A meningococcal conjugate vaccine: Future challenges and next steps

Human Vaccines & Immunotherapeutics, 2018
The introduction of a new Group A meningococcal conjugate vaccine, MenAfriVacR, has been a important public health success. Group A meningococcal meningitis has disappeared in all countries where the new Men A conjugate vaccine has been used at public ...
F. Marc LaForce, Mamoudou Djingarey, Simonetta Viviani, Marie-Pierre Preziosi   +3 more
doaj   +1 more source

Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis

Frontiers in Medicine, 2020
Neisseria meningitidis causes sepsis and meningitis in humans. It has been suggested that pathogen genetic variation determines variance in disease severity. Here we report results of a genome-wide association study of 486 N.
Philip H. C. Kremer, John A. Lees, John A. Lees, Bart Ferwerda, Bart Ferwerda, Arie van de Ende, Arie van de Ende, Matthijs C. Brouwer, Stephen D. Bentley, Diederik van de Beek   +9 more
doaj   +1 more source