Results 151 to 160 of about 498,582 (354)

Clinical presentation, treatment, and outcome of children with primary intestinal lymphangiectasia: A national retrospective study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Primary intestinal lymphangiectasia (PIL) is a very rare disease responsible for protein‐losing enteropathy. There is little published data about treatments efficacy and outcomes. Our main objective was to describe the clinical profile, response to therapy, and outcomes of children with PIL.
Noémie Goret, Cécile Lambe, Emmanuelle Ecochard‐Dugelay, Alexandre Fabre, Alain Dabadie, Aurélie Comte, Julie Rebeuh, Pierre Poinsot, Emilie Chaillou, Haude Clouzeau, Aurélie Sabard, Béatrice Dubern, Stéphanie Willot   +12 more
wiley   +1 more source

Impact of pneumococcal conjugate vaccines on invasive pneumococcal disease-causing lineages among South African children

Nature Communications
Invasive pneumococcal disease (IPD) due to non-vaccine serotypes after the introduction of pneumococcal conjugate vaccines (PCV) remains a global concern.
Cebile Lekhuleni, Kedibone Ndlangisa, Rebecca A. Gladstone, Sopio Chochua, Benjamin J. Metcalf, Yuan Li, Jackie Kleynhans, Linda de Gouveia, Scott Hazelhurst, Ana D. S. Ferreira, Happy Skosana, Sibongile Walaza, Vanessa Quan, Susan Meiring, Paulina A. Hawkins, Lesley McGee, Stephen D. Bentley, Cheryl Cohen, Stephanie W. Lo, Anne von Gottberg, Mignon du Plessis   +20 more
doaj   +1 more source

Characteristics of Adult Patients With Atopic Dermatitis Initiating Biologics and Janus Kinase Inhibitors in the CorEvitas Atopic Dermatitis Registry

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Biologics and Janus kinase inhibitors (JAKi) are two advanced systemic treatment options for patients with atopic dermatitis (AD). The decision to initiate one of these therapies is complex and may be driven by many factors.
Eric L. Simpson, Linda Stein Gold, Seemal R. Desai, Alexandra K. Golant, Douglas DiRuggiero, Christian Fenske, Yolanda Muñoz Maldonado, Alvin H. Li, Zach Dawson, Kaylee Ho, Kayla Callahan, Gaia Gallo, Jonathan I. Silverberg   +12 more
wiley   +1 more source

Contemporary Clinical Management of Otosyphilis for Practicing Otolaryngologists—A Scoping Review

The Laryngoscope, EarlyView.
Otosyphilis has reemerged alongside increasing syphilis rates, highlighting the need for early recognition to prevent severe audiovestibular complications. A scoping review and retrospective case series indicate that most patients present with hearing loss, tinnitus, or vertigo and typically respond to penicillin‐based treatment.
Corinne A. Pittman, Hudson Liu, Sandeep Kowkuntla, Erica Choe, Matthew J. Copeland, Michael Hoa, Selena Briggs, H. Jeffrey Kim   +7 more
wiley   +1 more source

Sterile Nasal Septal Abscess in Ulcerative Colitis With Crypt Abscess‐Like Neutrophilic Infiltration

The Laryngoscope, EarlyView.
We report a rare case of sterile nasal septal abscess in a patient with ulcerative colitis. Histopathological analysis revealed crypt abscess‐like neutrophilic infiltration in the nasal mucosal glands, resembling a typical feature of ulcerative colitis.
Masakazu Murayama, Yoshihito Tanaka, Tomoyuki Yokose, Toshikazu Shimane   +3 more
wiley   +1 more source

Cochlear Implantation and Facial Nerve Stimulation: Clinical and Anatomic Correlations

The Laryngoscope, EarlyView.
One rare complication of cochlear implantation (CI) is facial nerve stimulation (FNS) and in this study the location and insertion depths for electrode contacts causing FNS was analyzed, and the anatomical variance of the human facial nerve canal (FNC) was explored to elucidate the mechanisms underlying FNS.
Karin Hallin, Sumit Agrawal, Hanif M. Ladak, Helge Rask‐Andersen, Hao Li   +4 more
wiley   +1 more source

Unexpected pathogen presenting with purulent meningitis

, 2020
Jamie Bering, Carlos Hartmann, Kara Asbury, Holenarasipur R. Vikram   +3 more
openalex   +2 more sources

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Incidence and transmission of respiratory syncytial virus in urban and rural South Africa, 2017-2018

Nature Communications
Data on respiratory syncytial virus (RSV) incidence and household transmission are limited. To describe RSV incidence and transmission, we conducted a prospective cohort study in rural and urban communities in South Africa over two seasons during 2017 ...
Cheryl Cohen, Jackie Kleynhans, Jocelyn Moyes, Meredith L. McMorrow, Florette K. Treurnicht, Orienka Hellferscee, Nicole Wolter, Neil A. Martinson, Kathleen Kahn, Limakatso Lebina, Katlego Mothlaoleng, Floidy Wafawanaka, Francesc Xavier Gómez-Olivé, Thulisa Mkhencele, Azwifarwi Mathunjwa, Maimuna Carrim, Angela Mathee, Stuart Piketh, Brigitte Language, Anne von Gottberg, Stefano Tempia   +20 more
doaj   +1 more source

Dysfunctional Glymphatic System with Disrupted Aquaporin 4 Expression Pattern on Astrocytes Causes Bacterial Product Accumulation in the CSF during Pneumococcal Meningitis

, 2022
Jaqueline S. Generoso, Sigrun Thorsdottir, Allan Collodel, Diogo Dominguini, Roberta R. E. Santo, Fabrícia Petronilho, Tatiana Barichello, Federico Iovino   +7 more
openalex   +1 more source