Results 171 to 180 of about 156,276 (197)

Type I interferon signalling and interferon‐responsive microglia in health and disease

The FEBS Journal, EarlyView.
Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya, Aysha M. Bhojwani‐Cabrera   +1 more
wiley   +1 more source

Irregular and Infectious? COVID‐19, Ebola and the Securitization of Migration to Southern Europe

JCMS: Journal of Common Market Studies, EarlyView.
Abstract Securitization scholarship concentrates on the discursive association between undocumented migration, terrorism and crime. Our textual and visual analysis of Italian, Spanish and Maltese newspapers between 2013 and 2020 demonstrates that the discourses securitizing irregular mobility as a health risk became more salient than those linking ...
Eugenio Cusumano, Martina Abisso, Diego Caballero‐Vélez   +2 more
wiley   +1 more source

Switching PD‐1 to BRAF + MEK inhibition improves recurrence‐free survival in patients receiving a second course of adjuvant melanoma therapy

Journal of the European Academy of Dermatology and Venereology, EarlyView.
66 patients from 22 centers received adjuvant treatment after relapse under or after previous adjuvant therapy with BRAF + MEK or PD‐1. Data highlight a significant benefit when switching from PD‐1 to BRAF + MEK adjuvant therapy compared to a switch from BRAF + MEK to PD‐1 adjuvant regimens.
Katharina Schumann, Kai Christian Klespe, Cornelia Mauch, Carmen Loquai, Ulrike Schultheis, Sevil Börger, Alexander Thiem, Steffen Emmert, Magdalena Hoellwerth, Peter Kölblinger, Van Anh Nguyen, Marina Wanner, Erika Richtig, Wiebke K. Peitsch, Wolfgang Harth, Veronika Zenderowski, Andreas Dominik Braun, Miriam Mengoni, Reinhard Dummer, Johanna Mangana, Lara Valeska Maul, Frank Meiß, Klemens Rappersberger, Oana Diana Persa, Tilo Biedermann, Christian Posch   +25 more
wiley   +1 more source

Pneumococcus meningitis: recovery after treatment with serum and sulfapyridine

, 1940
Ewaldo Mario Russo
openalex   +2 more sources

A Severe Epidemic of Meningococcus Meningitis in Chile, 1941-1942

, 1944
Mario Pizzi
openalex   +2 more sources

Perspectives and Requirements of Patients with Prostate Cancer on Mobile Health Interventions During Androgen Deprivation Therapy: A Descriptive Qualitative Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To explore the perceptions of patients with prostate cancer undergoing androgen deprivation therapy towards mobile health interventions. Design The study employed a qualitative descriptive design. Methods Seventeen participants were recruited from tertiary care hospitals from November 2022 to June 2023. The collected data were subsequently
Hongfan Yin, Chen Pan, Jia Gu, Yan Yang
wiley   +1 more source

Glomerular ultrastructural change and vascular endothelial growth factor‐A expression in diabetic cats

Journal of Small Animal Practice, EarlyView.
Objectives To evaluate the glomerular ultrastructural changes associated with diabetic nephropathy and quantify glomerular vascular endothelial growth factor‐A expression in cats with diabetes mellitus compared to controls. Materials and Methods Transmission electron microscopy was performed to evaluate glomerular ultrastructural changes, including ...
H. Reyes‐Hughes, E. Bird, C. Neal, R. Noiva, R. R. Foster, S. Satchell, N. Finch   +6 more
wiley   +1 more source

Incorporating the Competencies of Evidence‐Based Veterinary Medicine Focused on Pharmacotherapeutics Into Clinical Rotations for Small Animal Dermatology and Food Animal Medicine and Surgery at a Veterinary Medical Teaching Hospital in the US

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Building the skills and knowledge necessary to practice evidence‐based veterinary medicine (EBVM) should occur throughout the veterinary curriculum. Operationalizing EBVM includes asking a clinical question in PICO format, searching the biomedical literature for evidence, critically appraising the evidence, and applying the evidence to make a ...
Virginia R. Fajt, Adam P. Patterson, Dusty Nagy, Jennifer Schleining, Kevin Washburn   +4 more
wiley   +1 more source

Is Rifampin (Rifampicin) Essential for the Treatment of Rhodococcus equi Infections in Foals? A Critical Review of the Role of Rifampin

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Rifampin is an enigma among antimicrobials. Blood and tissue compartment concentrations are a “moving target” along the treatment course due to the complex pharmacodynamic interactions within the body. Rifampin concomitant therapies are for the prevention and treatment of Rhodococcus equi infection in foals, for nearly 40 years.
Keith Edward Baptiste, Niels Christian Kyvsgaard, Mohamed Omar Ahmed, Peter Damborg, Patricia M. Dowling   +4 more
wiley   +1 more source

Modelling vector and host distributions to inform potential disease risk: A case study of West Nile virus in the United Kingdom

Medical and Veterinary Entomology, EarlyView.
Correlative modelling approaches can be used successfully to predict the distribution of vectors and hosts involved in vector‐borne diseases of concern. For West Nile virus in the United Kingdom, host distributions are unlikely to be a significant factor influencing change. Vector distributions and urbanisation will drive increasing risk. Projecting to
Amy J. Withers, Simon Croft, Richard Budgey, Daniel A. Warren, Nicholas Johnson   +4 more
wiley   +1 more source