Results 311 to 320 of about 494,505 (356)

Study of conditions to evaluate light hypersensitivity in a light–dark box using a mouse model and a mydriatic

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim The pathophysiology and treatment of sensory hypersensitivity remain unclear. This study aimed to identify a simple behavioral analysis device and animal model evaluating glare sensitivity and to test the effects of psychotropic drugs using this device.
Shogo Hirota   +7 more
wiley   +1 more source

Determinants of Prolonged Antibiotic Administration in Culture-Negative Evaluations of Early-Onset Neonatal Meningitis: A Retrospective Cohort Study. [PDF]

open access: yesAntibiotics (Basel)
Mesilhy R   +8 more
europepmc   +1 more source

Narsoplimab Results in Excellent Survival in Adults and Children With Hematopoietic Cell Transplant Associated Thrombotic Microangiopathy (TA‐TMA)

open access: yesAmerican Journal of Hematology, Volume 100, Issue 11, Page 2040-2051, November 2025.
ABSTRACT Inappropriate complement activation is a key driver of hematopoietic cell transplant‐associated thrombotic microangiopathy (TA‐TMA). Treatment with narsoplimab, an inhibitor of MASP‐2, the effector enzyme of the lectin pathway, resulted in a response rate of 61% in a Phase 2 clinical trial in adults with TA‐TMA.
Michelle L. Schoettler   +6 more
wiley   +1 more source

Actinobacillus ureae Meningitis in Pediatrics: A Rare Clinical Case. [PDF]

open access: yesCureus
Ouamna N   +4 more
europepmc   +1 more source

Comorbidities in Mild WAS/XLT Require Lifelong Follow‐Up and Consideration of Definitive Treatment

open access: yesAmerican Journal of Hematology, Volume 100, Issue 11, Page 2004-2016, November 2025.
Our study followed the clinical and biological course of 261 WAS/XLT patients, including 170 with a mild form of the disease. The occurrence of late complications even in mild patients confirms the importance of offering lifelong follow‐up and considering definitive treatment (HSCT/gene therapy) for all patients.
Coralie Mallebranche   +16 more
wiley   +1 more source

Genotype–Phenotype Correlations, Mortality, and Clinical Insights in Keratitis–Ichthyosis–Deafness Syndrome: A Comprehensive Review and Case Report

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero   +17 more
wiley   +1 more source

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