Results 51 to 60 of about 29,938 (169)

Age at First RSV Hospitalisation and the Risk of Subsequent Bacterial Pneumonia

open access: yes
Acta Paediatrica, EarlyView.
Samuel Videholm   +4 more
wiley   +1 more source

Analytical Insights into Protein–Alum Interactions and Their Impact on Conformational Epitope

open access: yesPharmaceutics
Several alum-adjuvanted vaccines have been licensed in the past 40 years. Despite its extensive and continuous use, the immune mechanism of action of alum adjuvants is not yet completely understood. Many different variables during the formulation process
Alessio Corrado   +7 more
doaj   +1 more source

Vaccine prevention of meningococcal disease in Africa: Major advances, remaining challenges

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Africa historically has had the highest incidence of meningococcal disease with high endemic rates and periodic epidemics. The meningitis belt, a region of sub-Saharan Africa extending from Senegal to Ethiopia, has experienced large, devastating ...
Mustapha M. Mustapha, Lee H. Harrison
doaj   +1 more source

Doença meningocócica: epidemiologia e controle dos casos secundários Meningococcal disease: epidemiology and control of secondary cases

open access: yesRevista de Saúde Pública, 1998
Aspectos epidemiológicos da doença meningocócica registrados a partir da segunda metade da década de 80 impulsionaram as autoridades de saúde pública a discutirem as medidas de controle disponíveis.
David E. Barroso   +3 more
doaj   +1 more source

The Current Landscape and Future Prospects of Vaccine Manufacturing in Africa: Challenges, Innovations, and Opportunities: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Africa has significant challenges in meeting its vaccination needs, including inadequate manufacturing capacity, infrastructure deficiencies, a scarcity of experienced personnel, regulatory hurdles, restricted access to technology and intellectual property.
Courage Chandipwisa   +3 more
wiley   +1 more source

Healthcare Development, Relaxed Natural Selection, and COVID‐19 Infection Rates: An Evolutionary Population‐Level Analysis

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aim Evolutionary principles offer critical insights into pandemic dynamics but have been largely overlooked in contemporary responses to COVID‐19. Relaxed natural selection, increased global mobility, and lifestyle mismatches have contributed to human vulnerability to infectious diseases in modern societies.
Wenpeng You   +5 more
wiley   +1 more source

Application of Causal Inference to Establish Assay Effect in the Absence of a Bridging Study: A Case Study of MenACWY‐CRM Conjugate Vaccine Data

open access: yesPharmaceutical Statistics, Volume 25, Issue 2, March/April 2026.
ABSTRACT During a vaccine development program, if the assay used to measure immunological endpoints is changed, ideally, a bridging study is performed to establish the relationship between results obtained with the new and previous assay. However, this is not always feasible, and when bridging study data are absent, this can limit the ability to use ...
Meike Adani   +4 more
wiley   +1 more source

Minimal Symptom Expression in Generalized Myasthenia Gravis: A Valuable Patient‐Centric Treatment Goal

open access: yesEuropean Journal of Neurology, Volume 33, Issue 3, March 2026.
Conceptual framework supporting Minimal Symptom Expression (MSE) as a patient‐centric treatment goal in generalized myasthenia gravis. Guidelines prioritize minimal manifestations (MM) or better (MGFA‐PIS); MM is clinician‐judgment based and not instrument‐defined. MSE (MG‐ADL 0‐1) is standardized, actionable, and widely used. Across Phase III programs
Andreas Meisel   +5 more
wiley   +1 more source

Identification of Neisseria Meningitidis in Patients with Suspected Meningitis: a Study in Imam Reza Hospital, Kermanshah City, Iran, 2013 [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2016
Background & Aims: Neisseria meningitidis is bacteria fastidious, and the main causes of meningitis and acute sepsis. Appropriate treatment depends on accurate and timely diagnosis. This study aimed to identify Neisseria meningitidis infection in samples
Alisha Akya   +2 more
doaj  

Gonorrhea Management in High‐, Limited‐ and No‐Resource Settings: Implications in the Context of Antimicrobial Resistance

open access: yesInternational Journal of Dermatology, Volume 65, Issue 3, Page 444-455, March 2026.
ABSTRACT Gonorrhea, a common sexually transmitted infection caused by Neisseria gonorrhoeae, represents an escalating global public health threat due to antimicrobial resistance. The current review explores diverse approaches around the globe to gonorrhea management across various settings, with a focus on diagnostic strategies, treatment practices ...
Andrei Tanasov   +2 more
wiley   +1 more source

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