What is the evidence for giving chemoprophylaxis to children or students attending the same preschool, school or college as a case of meningococcal disease? [PDF]
We performed a systematic literature review to assess the effectiveness of chemoprophylaxis for contacts of sporadic cases of invasive meningococcal disease (IMD) in educational settings.
Ackerman +30 more
core +2 more sources
Stewardship of Molecular Diagnostics in Transplant Viral Infections
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden +3 more
wiley +1 more source
Epidemiological Characteristics of Meningococcal Infection in Moscow
Aims. The purpose of this study was to identify current epidemiological features of meningococcal infection in Moscow.Materials and methods. Cases of invasive meningococcal disease in Moscow from 2014 to 2018 and the biomaterial from patients with an ...
M. I. Gritsay +3 more
doaj +1 more source
Dramatic decline of serogrup C meningococcal disease incidence in Catalonia (Spain) 24 months after a mass vaccination programme of children and young people [PDF]
STUDY OBJECTIVES The objective of this study was to evaluate the effectiveness of a mass vaccination programme carried out in Catalonia (Spain) in the last quarter of 1997 in response to an upsurge of serogroup C meningococcal disease (SCMD).
Domínguez García, Àngela +4 more
core +2 more sources
AbstractThe occurrence of arthritis with acute meningococcal infection is reviewed and eleven cases presented. The arthritis is usually oligoarticular, often appears when the systemic or meningeal infection is improving, may give rise to persistent purulent but sterile and relatively painless joint effusions, is not greatly influenced by antibacterial ...
R S, PINALS, M W, ROPES
openaire +2 more sources
Abstract Background and Objectives Hyperhaemolysis syndrome is a life‐threatening complication of transfusion, potentially triggered by macrophage activation, with limited treatment options. Tocilizumab, an anti‐IL6 monoclonal antibody, has mechanistic rationale for use and has been shown to be effective in a small number of cases.
S. Wolf +8 more
wiley +1 more source
High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia [PDF]
A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV‐8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV‐8 sVCA
Angeloni, Antonio +11 more
core +1 more source
ABSTRACT During a vaccine development program, if the assay used to measure immunological endpoints is changed, ideally, a bridging study is performed to establish the relationship between results obtained with the new and previous assay. However, this is not always feasible, and when bridging study data are absent, this can limit the ability to use ...
Meike Adani +4 more
wiley +1 more source
Adjuvants : an essential component of neisseria vaccines [PDF]
Adjuvants may be classified into delivery systems and immune potentiator or modulator molecules based on their mechanism of action. Neisseria vaccines containing traditional adjuvants such as aluminium salts have existed for long time, but meningitis ...
Acevedo, R. +8 more
core
Cocirculation of Hajj and non-Hajj strains among serogroup W meningococci in Italy, 2000 to 2016 [PDF]
In Italy, B and C are the predominant serogroups among meningococci causing invasive diseases. Nevertheless, in the period from 2013 to 2016, an increase in serogroup W Neisseria meningitidis (MenW) was observed.
Arghittu M. +16 more
core +1 more source

