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Meningococcal disease in Africa
Annals of Tropical Medicine And Parasitology, 1997Neisseria meningitidis (the meningococcus) is responsible for endemic and meningococcal disease in Africa. Meningococci are placed into 12 serogroups based on their capsular polysaccharide antigens. Group-B meningococci are responsible for sporadic endemic disease.
Luis E. Cuevas, C. A. Hart
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Meningococcal disease and travel
International Journal of Antimicrobial Agents, 2003Meningococcal disease continues to be a worldwide problem. This review examines the impact meningococcal disease has on international travel and vice versa the impact international travel has on the intercontinental spread of meningococci. The risk of meningococcal disease to the endemic population differs from that of travellers.
Ziad A. Memish, Annelies Wilder-Smith
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Influenza A and meningococcal disease
The Lancet, 1991There are several anecdotal accounts of the association between outbreaks of influenza and meningococcal disease. The exceptional increase in the number of cases of meningococcal infection 2 weeks after an influenza A outbreak in England and Wales during November and December, 1989, provided an opportunity to investigate the relation between the two ...
J. M. Stuart +5 more
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Meningococcal disease in Italy
Journal of Infection, 1989In 1985, nationwide surveillance of meningococcal disease aimed at establishing appropriate guidelines for prophylaxis started in Italy. The incidence of disease was 1.1/100,000 in 1985 and 0.6/100,000 in 1987. This decreasing trend was particularly evident among military recruits (from 17.3/100,000 in 1985 to 5/100,000 in 1987), reflecting the use of ...
Occhionero M +3 more
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Science, 2003
The human-specific bacterial pathogen Neisseria meningitidis is a major cause of sepsis and/or meningitis. The pili of N. meningitidis interact with CD46, a human cell-surface protein involved in regulation of complement activation.
Peter Bergman +8 more
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The human-specific bacterial pathogen Neisseria meningitidis is a major cause of sepsis and/or meningitis. The pili of N. meningitidis interact with CD46, a human cell-surface protein involved in regulation of complement activation.
Peter Bergman +8 more
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JAMA: The Journal of the American Medical Association, 1966
Within the last two years there have been many isolations of sulfonamide-resistant meningococci from military and civilian populations. This probably reflects the current prevalence of groups B and C. There is evidence that these serotypes had varying degrees of resistance more than 20 years ago.
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Within the last two years there have been many isolations of sulfonamide-resistant meningococci from military and civilian populations. This probably reflects the current prevalence of groups B and C. There is evidence that these serotypes had varying degrees of resistance more than 20 years ago.
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Management of meningococcal disease
Paediatrics and Child Health, 2011Abstract Despite introduction of effective vaccines, meningococcal disease remains a life-threatening illness with significant mortality, morbidity and long term sequelae. Prompt recognition and early treatment with antibiotics and recognition and aggressive management of complications such as shock and raised intracranial pressure are imperative ...
Avishay Sarfatti, Simon Nadel
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Albumin in meningococcal disease
Hospital Medicine, 2000The management of acute meningococcal disease (MD) exemplifies what is best and worst about modern paediatric intensive care. The best because, in the face of well-staffed teams with centralized experience, survival has improved dramatically (clinical scoring systems such as the Glasgow Meningococcal Septicaemia Prognostic Score indicate that for the ...
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Epidemiology of meningococcal disease
Hospital Medicine, 2002In the UK, serogroup A strains disappeared 50years ago, but in the 1990s, numbers of cases rose again to a 50-year high. Following the very successful introduction of conjugated meningitis C vaccines, effective meningitis B vaccines are now the highest priority.
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