Results 61 to 70 of about 8,977,908 (300)

Epidemiology and Regional Programs on Meningococcal Disease Prevention in Tyumen Region and Yamalo-Nenets Autonomous District

open access: yesВопросы современной педиатрии, 2020
Meningococcal disease is the urgent problem of healthcare due to its widespread prevalence, high incidence, severe course and high risk of mortality. Vaccination of Russian Federation population with polyvalent meningococcal vaccine for serogroups A, C ...
Olga A. Richkova   +7 more
doaj   +1 more source

Clinical Outcomes and Treatment Strategies of Adult Transplant‐Associated Thrombotic Microangiopathy: External Validation of Harmonizing Definitions and High‐Risk Criteria

open access: yesAmerican Journal of Hematology, Volume 100, Issue 5, Page 830-839, May 2025.
ABSTRACT Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an endothelial dysfunction syndrome observed after allogeneic hematopoietic cell transplant (alloHCT). Our aim was to externally validate the impact of high‐risk features on the clinical outcomes of adult patients meeting the updated TA‐TMA harmonizing criteria. Between 2005 and 2022,
Aldo A. Acosta‐Medina   +19 more
wiley   +1 more source

Epidemiology of Meningococcal Disease Outbreaks in the United States, 2009–2013

open access: yesClinical Infectious Diseases, 2018
Background Although the incidence of meningococcal disease is low in the United States, outbreaks remain a serious public health concern. In this evaluation, we identify and describe outbreaks of meningococcal disease. Methods A retrospective review of
Sarah A Mbaeyi   +5 more
semanticscholar   +1 more source

Neisseria meningitidis accumulate in large organs during meningococcal sepsis

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
BackgroundNeisseria meningitidis (Nm) is the cause of epidemic meningitis and fulminant meningococcal septicemia. The clinical presentations and outcome of meningococcal septic shock is closely related to the circulating levels of lipopolysaccharides ...
Berit Sletbakk Brusletto   +5 more
doaj   +1 more source

The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]

open access: yes, 2013
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified ...
arxiv   +1 more source

Unveiling new disease, pathway, and gene associations via multi-scale neural networks [PDF]

open access: yesPLOS ONE, 15(4), p.e0231059 (2020), 2019
Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can be derived from a patient cell's profile, improving our diagnosis ability, as well as our grasp of disease risks ...
arxiv   +1 more source

Beta‐Lactam Antibiotics Promote Extracellular Vesicle Production of Staphylococcus aureus Through ROS‐Mediated Lipid Metabolic Reprogramming

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 5, May 2025.
ABSTRACT Bacterial extracellular vesicles (EVs) are natural reservoirs of biological active substances. They exhibit promising application in developing bioproducts such as vaccine, drug‐delivery system and anticancer agent. However, the low yield of naturally secreted EVs during bacterial growth is a bottleneck factor that restricts EV applications ...
Xiaonan Huang   +20 more
wiley   +1 more source

Systemic manifestations in the course of meningococcal disease [PDF]

open access: yesVojnosanitetski Pregled, 2009
Background/Aim. Meningococcal disease most often manifests itself as meningitis or sepsis. During the course of these diseases, other clinical events sometimes develop such as pneumonia, pericarditis, arthritis, and they are referred to as extrameningeal
Dulović Olga   +7 more
doaj   +1 more source

Meningococcal disease and meningitis

open access: yesJornal de Pediatria, 2007
To review the literature relevant to diagnosis and management of meningococcal disease (MD).Non-systematic review of medical literature through the MEDLINE database using the terms meningococcal, septic shock, diagnosis, and treatment. Articles were selected according to their relevance to the objective of the study and according to the authors ...
Ricardo Garcia Branco   +2 more
openaire   +2 more sources

Childhood Vaccine Hesitancy as an Interaction‐Based Phenomenon

open access: yesSociology of Health &Illness, Volume 47, Issue 4, May 2025.
ABSTRACT The paper discusses the role of the interaction between parents and healthcare professionals in overcoming or heightening childhood vaccine hesitancy. Childhood vaccine hesitancy is seen as a set of attitudes and behaviours—that is, dispositions—that are highly dependent on how trust and vulnerability intersect during vaccination appointments.
Alice Scavarda   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy