Results 61 to 70 of about 8,977,908 (300)
Meningococcal disease is the urgent problem of healthcare due to its widespread prevalence, high incidence, severe course and high risk of mortality. Vaccination of Russian Federation population with polyvalent meningococcal vaccine for serogroups A, C ...
Olga A. Richkova+7 more
doaj +1 more source
ABSTRACT Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an endothelial dysfunction syndrome observed after allogeneic hematopoietic cell transplant (alloHCT). Our aim was to externally validate the impact of high‐risk features on the clinical outcomes of adult patients meeting the updated TA‐TMA harmonizing criteria. Between 2005 and 2022,
Aldo A. Acosta‐Medina+19 more
wiley +1 more source
Epidemiology of Meningococcal Disease Outbreaks in the United States, 2009–2013
Background Although the incidence of meningococcal disease is low in the United States, outbreaks remain a serious public health concern. In this evaluation, we identify and describe outbreaks of meningococcal disease. Methods A retrospective review of
Sarah A Mbaeyi+5 more
semanticscholar +1 more source
Neisseria meningitidis accumulate in large organs during meningococcal sepsis
BackgroundNeisseria meningitidis (Nm) is the cause of epidemic meningitis and fulminant meningococcal septicemia. The clinical presentations and outcome of meningococcal septic shock is closely related to the circulating levels of lipopolysaccharides ...
Berit Sletbakk Brusletto+5 more
doaj +1 more source
The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified ...
arxiv +1 more source
Unveiling new disease, pathway, and gene associations via multi-scale neural networks [PDF]
Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can be derived from a patient cell's profile, improving our diagnosis ability, as well as our grasp of disease risks ...
arxiv +1 more source
ABSTRACT Bacterial extracellular vesicles (EVs) are natural reservoirs of biological active substances. They exhibit promising application in developing bioproducts such as vaccine, drug‐delivery system and anticancer agent. However, the low yield of naturally secreted EVs during bacterial growth is a bottleneck factor that restricts EV applications ...
Xiaonan Huang+20 more
wiley +1 more source
Systemic manifestations in the course of meningococcal disease [PDF]
Background/Aim. Meningococcal disease most often manifests itself as meningitis or sepsis. During the course of these diseases, other clinical events sometimes develop such as pneumonia, pericarditis, arthritis, and they are referred to as extrameningeal
Dulović Olga+7 more
doaj +1 more source
Meningococcal disease and meningitis
To review the literature relevant to diagnosis and management of meningococcal disease (MD).Non-systematic review of medical literature through the MEDLINE database using the terms meningococcal, septic shock, diagnosis, and treatment. Articles were selected according to their relevance to the objective of the study and according to the authors ...
Ricardo Garcia Branco+2 more
openaire +2 more sources
Childhood Vaccine Hesitancy as an Interaction‐Based Phenomenon
ABSTRACT The paper discusses the role of the interaction between parents and healthcare professionals in overcoming or heightening childhood vaccine hesitancy. Childhood vaccine hesitancy is seen as a set of attitudes and behaviours—that is, dispositions—that are highly dependent on how trust and vulnerability intersect during vaccination appointments.
Alice Scavarda+2 more
wiley +1 more source