The changing face of meningococcal infection. [PDF]
Menigococcal infection is caused by Neisseria meningitidis, a Gram negative diplococci. Invasive meningococcal disease (IMD) is caused by 6 capsular groups. The spectrum of infection is broad, with meningitis and meningococcal sepsis associated with a case fatality of between 4 and 20%.
Knapper F.
europepmc +5 more sources
Hydrocephalus and Cerebral Small Vessel Disease in an Adult With Meningococcal Meningitis and Dilated Cardiomyopathy: A Fatal Outcome. [PDF]
ABSTRACT Meningococcal meningitis can lead to serious neurological complications such as hydrocephalus directly and contribute to cerebral small vessel disease indirectly, especially in patients with pre‐existing conditions like dilated cardiomyopathy.
Mohamed Y+3 more
europepmc +2 more sources
Revealing the molecular signatures of host-pathogen interactions. [PDF]
Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co ...
C Herdtweck+53 more
core +18 more sources
Treatment of meningococcal infection [PDF]
Aggressive early treatment of meningococcal disease can reduce mortality. This relies on prompt recognition and treatment of the complications of septicaemia and meningitis, appropriate ongoing intensive care where necessary, and adequate management of multiple organ failure.
S B Welch, S Nadel
openaire +3 more sources
Meningococcal Disease in Patients With Human Immunodeficiency Virus Infection: A Review of Cases Reported Through Active Surveillance in the United States, 2000-2008. [PDF]
BackgroundAlthough human immunodeficiency virus (HIV) infection is an established risk factor for several bacterial infections, the association between HIV infection and meningococcal disease remains unclear.MethodsExpanded chart reviews were completed ...
Clark, Thomas A+17 more
core +2 more sources
Detection of the United States Neisseria meningitidis urethritis clade in the United Kingdom, August and December 2019 - emergence of multiple antibiotic resistance calls for vigilance. [PDF]
Since 2015 in the United States (US), the US Neisseria meningitidis urethritis clade (US_NmUC) has caused a large multistate outbreak of urethritis among heterosexual males.
Borrow, R+12 more
core +2 more sources
Invasive meningococcal disease in the Veneto region of Italy: A capture-recapture analysis for assessing the effectiveness of an integrated surveillance system [PDF]
open8noBACKGROUND: Epidemiology of Neisseria meningitidis has been changing since the introduction of universal vaccination programmes against meningococcal serogroup C (MenC) and meningococcal serogroup B (MenB) has now become dominant.
Baldo, Vincenzo+7 more
core +1 more source
Human genetics of meningococcal infections [PDF]
AbstractNeisseria meningitidisis a leading cause of bacterial septicaemia and meningitis worldwide. Meningococcal disease is rare but can be life threatening with a tendency to affect children. Many studies have investigated the role of human genetics in predisposition toN. meningitidisinfection. These have identified both rare single-gene mutations as
Stephanie Hodeib+3 more
openaire +5 more sources
Māori and community news constructions of Meningococcal B: the promotion of a moral obligation to vaccinate [PDF]
News media communicate various risks of disease, showcase medical breakthroughs and disseminate texts that both reflect and renegotiate shared cultural understandings of health and illness. Little is known about the role of Māori and community news media
Chamberlain, Kerry+5 more
core +2 more sources
Complement and meningococcal infection. [PDF]
Serum C3 levels were measured in 211 patients with meningococcal disease. Low levels were found in 13 patients with acute meningococcaemia, and complement activation may have contributed to the peripheral circulatory collapse that was responsible for nine deaths.
Brian Greenwood+2 more
openaire +3 more sources