Risk and protective factors for meningococcal disease in adolescents: matched cohort study [PDF]
Objective: To examine biological and social risk factors for meningococcal disease in adolescents. Design: Prospective, population based, matched cohort study with controls matched for age and sex in 1:1 matching.
Booth, C.+9 more
core
Development of a SimpleProbe real-Time PCR Assay for rapid detection and identification of the US novel urethrotropic clade of Neisseria meningitidis ST-11 (US_NmUC) [PDF]
Urethritis, or inflammation of the urethra, is one of the most common reasons men seek clinical care. Sexually transmitted pathogens including Neisseria gonorrhoeae are responsible for over half of the symptomatic urethritis cases in U.S. men.
Ermel, Aaron+4 more
core +1 more source
Summary Shift work can cause circadian misalignment, which often results in sleeping problems and has been associated with immune dysfunction. To better understand the impact of shift work on a primary immune response to vaccination, we compared severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)‐specific humoral and cellular immune responses ...
Tamara M. J. Brouwers+14 more
wiley +1 more source
Upper respiratory tract infection heterologous immunization and meningococcal disease [PDF]
To test the hypothesis that an episode of upper respiratory tract infection or heterologous immunisation is a predisposing factor for the occurrence of meningococcal disease, data from 377 cases of meningococcal disease and their household contacts (n ...
Bijlmer, H.A.+4 more
core +2 more sources
Oropharyngeal Adverse Events to Drugs and Vaccines: Pharmacovigilance Data From Italy (2019–2021)
ABSTRACT Objectives The aim of this study was to perform a descriptive analysis of oropharyngeal adverse events (AEs) related to drugs and/or vaccines in order to provide useful information for clinicians. Methods Data related to three regions of Italy were analyzed from 2019 to 2021 by using the National Pharmacovigilance database.
Liberata Sportiello+16 more
wiley +1 more source
A space-time conditional intensity model for infectious disease occurence [PDF]
A novel point process model continuous in space-time is proposed for infectious disease data. Modelling is based on the conditional intensity function (CIF) and extends an additive-multiplicative CIF model previously proposed for discrete space epidemic ...
Assunçáo+26 more
core +3 more sources
Bacterial Outer Membrane Vesicles: From Physics to Clinical
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou+7 more
wiley +1 more source
Can near real-time monitoring of emergency department diagnoses facilitate early response to sporadic meningococcal infection? - prospective and retrospective evaluations [PDF]
Background Meningococcal infection causes severe, rapidly progressing illness and reporting of cases is mandatory in New South Wales (NSW), Australia.
Churches, Tim+3 more
core +3 more sources
ABSTRACT Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an endothelial dysfunction syndrome observed after allogeneic hematopoietic cell transplant (alloHCT). Our aim was to externally validate the impact of high‐risk features on the clinical outcomes of adult patients meeting the updated TA‐TMA harmonizing criteria. Between 2005 and 2022,
Aldo A. Acosta‐Medina+19 more
wiley +1 more source
Penicillin Use in Meningococcal Disease Management: Active Bacterial Core Surveillance Sites, 2009. [PDF]
In 2009, in the Active Bacterial Core surveillance sites, penicillin was not commonly used to treat meningococcal disease. This is likely because of inconsistent availability of antimicrobial susceptibility testing and ease of use of third-generation ...
Anderson, Raydel+18 more
core +2 more sources