Results 51 to 60 of about 1,730,732 (217)

Neisseria meningitidis accumulate in large organs during meningococcal sepsis

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundNeisseria meningitidis (Nm) is the cause of epidemic meningitis and fulminant meningococcal septicemia. The clinical presentations and outcome of meningococcal septic shock is closely related to the circulating levels of lipopolysaccharides ...
Berit Sletbakk Brusletto, Bernt Christian Hellerud, Reidun Øvstebø, Petter Brandtzaeg, Petter Brandtzaeg, Petter Brandtzaeg   +5 more
doaj   +1 more source

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

A Seroepidemiological Study of Serogroup A Meningococcal Infection in the African Meningitis Belt.

PLoS ONE, 2016
The pattern of epidemic meningococcal disease in the African meningitis belt may be influenced by the background level of population immunity but this has been measured infrequently.
Olivier Manigart, Caroline Trotter, Helen Findlow, Abraham Assefa, Wude Mihret, Tesfaye Moti Demisse, Biruk Yeshitela, Isaac Osei, Abraham Hodgson, Stephen Laryea Quaye, Samba Sow, Mamadou Coulibaly, Kanny Diallo, Awa Traore, Jean-Marc Collard, Rahamatou Moustapha Boukary, Oumarou Djermakoye, Ali Elhaji Mahamane, Jean-François Jusot, Cheikh Sokhna, Serge Alavo, Souleymane Doucoure, El Hadj Ba, Mariétou Dieng, Aldiouma Diallo, Doumagoum Moto Daugla, Babatunji Omotara, Daniel Chandramohan, Musa Hassan-King, Maria Nascimento, Arouna Woukeu, Ray Borrow, James M Stuart, Brian Greenwood   +33 more
doaj   +1 more source

Update on Selected Adverse Events of Concern Following Immunization With Acellular Pertussis Vaccines, a Narrative Review

Acta Paediatrica, Volume 115, Issue 11, Page 2370-2379, November 2026.
ABSTRACT Aim To provide an update paper on evidence of adverse events of concern following immunization (AEFI) with pertussis vaccines, focusing primarily on acellular (aP) vaccines. Methods Evidence was synthesised from epidemiological studies, systematic reviews over recent decades, expert interpretations in reviews from relevant research teams and ...
Lennart Nilsson, Jann Storsaeter
wiley   +1 more source

Sampling methods to detect carriage of Neisseria meningitidis; literature review.

, 2009
OBJECTIVES: Studies of meningococcal carriage are important in understanding the epidemiology of meningococcal disease and the impact of vaccination programmes. However, microbiological sampling methods to determine pharyngeal carriage are not consistent
Stuart, James, Roberts, Jonathan, Greenwood, Brian   +2 more
core   +1 more source

Eculizumab and ravulizumab clinical trial and real-world pharmacovigilance of meningococcal infections across indications.

PLoS ONE
IntroductionComplement component 5 inhibitor therapies (C5ITs) for rare hematological, renal, and neurological diseases are associated with increased meningococcal infection risk. Robust risk mitigation measures include vaccination, drug safety programs,
Cynthia Carrillo Infante, Arshad Mujeebuddin   +1 more
doaj   +1 more source

Trained Immunity in Childhood Vaccination

Acta Paediatrica, Volume 115, Issue 11, Page 2402-2413, November 2026.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source

Early diagnosis model for meningitis supports public health decision making.

, 2011
OBJECTIVE: To develop a predictive model for rapid differential diagnosis of meningitis and meningococcal septicaemia to support public health decisions on chemoprophylaxis for contacts.
Ejidokun, Oluwatoyin O, Meltzer, Margie, Neville Q. Verlander, Fraser, Graham, Meltzer, M, Oluwatoyin O. Ejidokun, Rehman, Yasmin, Verlander, Neville Q, Ninis, Nelly, Margie Meltzer, Nelly Ninis, Muir, Peter, Fraser, G, Verlander, NQ, Rehman, Y, Close, RM, James M. Stuart, Graham Fraser, Peter Muir, Muir, P, Stuart, James M, Stuart, JM, Rebecca M. Close, Yasmin Rehman, Close, Rebecca M, Ejidokun, OO   +25 more
core   +1 more source

Environmental risk and meningitis epidemics in Africa. [PDF]

, 2003
Epidemics of meningococcal meningitis occur in areas with particular environmental characteristics. We present evidence that the relationship between the environment and the location of these epidemics is quantifiable and propose a model based on ...
Stephen J. Connor, Anna M. Molesworth, Molesworth, Anna M., Connor, Stephen J, Connor, Stephen J., Thomson, Madeleine C., Cuevas, Luis E, Morse, Andrew P., Molesworth, Anna M, Andrew P. Morse, Luis E. Cuevas, Thomson, Madeleine C, Morse, Andrew P, Madeleine C. Thomson, Cuevas, Luis   +14 more
core   +1 more source

Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis

mBio, 2018
Pediatric meningococcal sepsis often results in morbidity and/or death, especially in young children. Our understanding of the reasons why young children are more susceptible to both the meningococcal infection itself and a more fulminant course of the ...
Noortje de Haan, Navin P. Boeddha, Ebru Ekinci, Karli R. Reiding, Marieke Emonts, Jan A. Hazelzet, Manfred Wuhrer, Gertjan J. Driessen   +7 more
doaj   +1 more source