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Meningococcal infection in children [PDF]

open access: possibleIrish Journal of Medical Science, 1988
TWO hundred and seventy five cases of meningococcal meningitis and/or septicaemia treated at the Children’s Hospital Temple Street, Dublin between January 1970 and December 1986 were retrospectively reviewed. Peak incidence was in 1981 (50 cases) and these cases were reviewed in greater detail.
K. Noordin, Denis Gill
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Meningococcal Infections in Children

New England Journal of Medicine, 1958
THE clinical evaluation of new antibacterial agents has resulted in varied recommendations for treatment of meningococcal infection.1 2 3 4 Clinical response to sulfonamides5 6 7 is superior to that with penicillin,8 9 10 11 12 13 and it has also been demonstrated that chloramphenicol3 and the tetracyclines14 are effective against this organism.
Merl J. Carson, Richard Koch
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Pachymeningitis after meningococcal infection

The Lancet, 2013
Department of Paediatrics and Infectious Disease (J Toubiana PhD, C Heilbronner MD, Prof D Gendrel MD), Department of Paediatrics and Neurology (C Gitiaux MD), Department of Paediatric Intensive Care Unit (M Oualha MD), and Study Centre for Primary Immunodefi ciencies (C Picard PhD), Necker Hospital, Descartes University, Paris, France; Infection ...
Toubiana, Julie   +8 more
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Meningococcal infections

2010
Abstract Neisseria meningitidis is an obligate human Gram-negative diplococcus. It is carried in the nasopharynx by about 3–10% of people, with most strains being harmless and inducing immunity. Pathogenic strains usually belong to specific clones that are encapsulated, express pili, and the major porin, PorA.
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Mortality in Meningococcal Infections

Scandinavian Journal of Infectious Diseases, 1978
Among 124 patients with meningococcal infections between 1966-1976, 108 had meningitis with a fatality rate of 7.4%, and 16 septicaemia with 18.8% fatality. High risk patients (more than 3 prognostically unfavourable characteristics) increased from 3.5% 1966-1970 to 15.6% 1971-1976, and the total mortality from 3.6 to 10.4%.
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Antibiotics for preventing meningococcal infections

2004
Meningococcal disease is a contagious bacterial disease caused by Neisseria meningitidis (N. meningitidis). Household contacts have the highest documented risk of the disease during the first seven days of a case being detected. Prophylaxis is, therefore, considered for those in close contact with people with a meningococcal infection and in ...
A, Fraser   +3 more
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Classification and Pathogenesis of Meningococcal Infections

2011
The clinical symptoms induced by Neisseria meningitidis reflect compartmentalized intravascular and intracranial bacterial growth and inflammation. In this chapter, we describe a classification system for meningococcal disease based on the nature of the clinical symptoms.
Brandtzaeg, P., Deuren, M. van
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MYOCARDITIS AND PERICARDITIS IN MENINGOCOCCIC INFECTIONS

Archives of Pediatrics & Adolescent Medicine, 1948
CHEMOTHERAPY, by reducing the early mortality in meningococcic disease, allows the appearance of late complications. The 13 year old girl whose illness is reported survived the early days of her disease with the aid of chemotherapy, but severe cardiac complications developed. A review of the literature has failed to reveal reports of any other child in
Charles Upton Lowe, Louis K. Diamond
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Treating meningococcal infections in children

Hospital Medicine, 2002
Aggressive early treatment of meningococcal disease in children can reduce mortality. This relies on prompt recognition of septicaemia and meningitis, and treatment of the complications of shock and raised intracranial pressure.
Simon Nadel, Steven B Welch
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