Results 21 to 30 of about 15,719 (229)

Public policy for meningococcal vaccination

open access: yesHuman Vaccines & Immunotherapeutics, 2018
On an individual basis, meningococcal disease is consistently shown to be one of the most feared potential childhood infections. On a population level, any clustering of cases or increase in disease requires proactive health protection management, while ...
J. Claire Cameron
doaj   +1 more source

Is primary meningococcal arthritis in children more frequent than we expect? Two pediatric case reports revealed by molecular test

open access: yesBMC Infectious Diseases, 2018
Background Primary meningococcal arthritis is a rare infectious disease that occurs in less than 3% of meningococcal infections and is characterized by arthritis without meningitis, fever, rash, or hemodynamic instability Barahona [Case Rep Orthop ...
S. Ricci   +6 more
doaj   +1 more source

A severe course of serogroup W meningococcemia in a patient with infantile nephropathic cystinosis

open access: yesHuman Vaccines & Immunotherapeutics, 2020
We present a 9-month old boy with cystinosis admitted to our hospital with the complaints of vomiting, diarrhea and seizure. While he was hospitalized in a pediatric intensive care unit due to worsening of his signs related to cystinosis, within hours ...
Gurkan Bozan   +7 more
doaj   +1 more source

Doença meningocócica em crianças: Panorama das hospitalizações e da morbimortalidade na Bahia e macrorregiões, de 2011 a 2020

open access: yesResidência Pediátrica, 2023
OBJECTIVE: To describe the epidemiological profile of hospitalizations of children due to meningococcal disease in Bahia and its macro-regions, estimating morbidity and mortality due to the disease.
Vitória Pinho Lopes Cunha   +3 more
doaj   +1 more source

Serum bactericidal activity against circulating and reference strains of meningococcal serogroup B in the United States: A review of the strain coverage of meningococcal serogroup B (MenB) vaccines in adolescents and young adults

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Invasive meningococcal disease (IMD) is rare but associated with high morbidity and mortality. In the United States, the most vulnerable age groups are infants and adolescents/young adults, and the most common type of IMD is caused by serogroup B (MenB).
Jessica Presa   +4 more
doaj   +1 more source

Endotoxin in meningococcal infections. [PDF]

open access: yesArchives of Disease in Childhood, 1980
26 children with meningococcal infections were studied to find out the relationaship between plasma and cerebrospinal fluid levels of endotoxin, the clinical outcome, the level of antigen in plasma and cerebrospinal fluid, and indices of complement activation and disseminated intravascular coagulation.
openaire   +3 more sources

The attitudes, behaviors, and knowledge of healthcare professionals towards the diagnosis, treatment, and prevention of bacterial meningitis in Turkey

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Introduction: Bacterial meningitis is one of the leading causes of morbidity and mortality among children and adults. Better understanding of the seroepidemiology of meningitis is critical for both the selection and implementation of an effective ...
Meltem Dinleyici   +5 more
doaj   +1 more source

N. meningitidis and TLR Polymorphisms: A Fascinating Immunomodulatory Network

open access: yesVaccines, 2016
N. meningitidis infections represent a global health problem that can lead to the development of serious permanent sequelae. Although the use of antibiotics and prevention via vaccination have reduced the incidence of meningococcal disease, our ...
Elena Gianchecchi   +4 more
doaj   +1 more source

Confirmation of Fixed Quarterly Riliprubart Regimen in Patients with Cold Agglutinin Disease Using Population PK/PD and Exposure‐Response Analyses

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Riliprubart is a second‐generation, humanized immunoglobulin G4 that inhibits only the activated form of the C1s component of the proximal classical complement pathway. The clinical studies of riliprubart conducted thus far for the treatment of cold agglutinin disease (CAD), a rare autoimmune disease, include a Phase 1 first‐in‐human study in healthy ...
Timothy Chow   +3 more
wiley   +1 more source

Harnessing the therapeutic potential of bacterial extracellular vesicles via functional peptides

open access: yesInterdisciplinary Medicine, EarlyView.
Bacterial extracellular vesicles (BEVs) are increasingly exploited as therapeutic agents or delivery vehicles for disease treatment due to their intrinsic structure, delivery capacity, immunogenic property, facile production, and versatile modification.
Yejiao Shi   +3 more
wiley   +1 more source

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