Results 21 to 30 of about 24,426 (207)

Evidence for Multi-Organ Infection During Experimental Meningococcal Sepsis due to ST-11 Isolates in Human Transferrin-Transgenic Mice

Microorganisms, 2020
The description of invasive meningococcal disease that is provoked by Neisseria meningitidis (Nm) is frequently restricted to meningitis. However, a wide panel of clinical presentations can be encountered including severe forms with intense inflammatory ...
Michael Levy, Myriam Aouiti Trabelsi, Muhamed-Kheir Taha   +2 more
doaj   +1 more source

Exploring the Ability of Meningococcal Vaccines to Elicit Mucosal Immunity: Insights from Humans and Mice

Pathogens, 2021
Neisseria meningitidis causes a devastating invasive disease but is also a normal colonizer of the human nasopharynx. Due to the rapid progression of disease, the best tool to protect individuals against meningococcal infections is immunization. Clinical
Elissa G. Currie, Scott D. Gray-Owen
doaj   +1 more source

Meningococcal disease in children in Merseyside, England : a 31 year descriptive study [PDF]

, 2011
Meningococcal disease (MCD) is the leading infectious cause of death in early childhood in the United Kingdom, making it a public health priority. MCD most commonly presents as meningococcal meningitis (MM), septicaemia (MS), or as a combination of the ...
Hart, C. Anthony, Marzouk, Omnia, Michelle C Stanton, Alistair P. J. Thomson, Paul B Baines, Hackett Scott J., Riordan F. Andrew I., Taylor-Robinson, David, Scott J. Hackett, Carrol, Enitan D., Peter J Diggle, Peter J. Diggle, Taylor-Robinson David, Baines, Paul B., Stanton Michelle C., Baines Paul B., Riordan, F. Andrew I., Thomson, Alistair P. J., Stanton, Michelle C., F Andrew I Riordan, Alistair P J Thomson, Nick Makwana, Paize, Fauzia, David Taylor-Robinson, David Harris, Michelle C. Stanton, Diggle Peter J., F. Andrew I. Riordan, Makwana Nick, Fauzia Paize, Harris David, Scott J Hackett, C Anthony Hart, Enitan D. Carrol, Makwana, Nick, Paize Fauzia, Paul B. Baines, Thomson Alistair P. J., Marzouk Omnia, Harris, David, Hart C. Anthony, C. Anthony Hart, Hackett, Scott J., Diggle, Peter J., Omnia Marzouk, Carrol Enitan D., Enitan D Carrol   +46 more
core   +1 more source

Meningococcal and pneumococcal meningitis in Northern Ghana [PDF]

, 2008
Despite improvements in technology, treatments and understanding of how bacterial meningitis develops, the disease remains a potentially life-threatening emergency capable of causing significant morbidity and mortality. N. meningitidis, S.
Forgor, Abdulai Adams
core   +1 more source

Molecular epidemiology of meningococcal disease in Northern Ghana [PDF]

, 2001
Meningococcal disease remains a major public health concern, especially in the African Meningitis Belt where large meningitis epidemics with attack rates of up to 500/100,000 recur every 8-12 years.
Gagneux, Sébastien
core   +1 more source

A Double Whammy Pneumonia: The First Reported Case of Concurrent and SARS-CoV-2 Pneumonia

Journal of Investigative Medicine High Impact Case Reports, 2022
Meningococcal pneumonia (MP) is a rare manifestation of meningococcal disease. The MP was first described in 1907 when Neisseria meningitidis (NM) isolates were identified in sputum samples obtained from soldiers with pneumonia.
Michael Valdez MD, Rupam Sharma MD, Jaspreet Joshi MS4, Harleen Sandhu MD, Shikha Mishra MD, Rasha Kuran MD, Arash Heidari MD   +6 more
doaj   +1 more source

Transmissibility and pathogenicity of the emerging meningococcal serogroup W sequence type-11 complex South American strain: a mathematical modeling study

BMC Medicine, 2020
Background The recent emergence of strains belonging to the meningococcal serogroup W (MenW) sequence type-11 clonal complex and descending from the South American sub-lineage (MenW:cc11/SA) has caused significant shifts in the epidemiology of ...
Matthieu Domenech de Cellès, Helen Campbell, Ray Borrow, Muhamed-Kheir Taha, Lulla Opatowski   +4 more
doaj   +1 more source

Sibling familial risk ratio of meningococcal disease in UK Caucasians. [PDF]

, 2003
To quantify the host genetic component of meningococcal disease (MD) susceptibility, the sibling risk ratio (lambdaS) was calculated as the ratio of observed MD cases among 845 siblings of 443 UK Caucasian cases to that expected, calculated from age ...
Haralambous, E, Hibberd, ML, Levin, M, Weiss, HA, Radalowicz, A, Booy, R   +5 more
core   +1 more source

Differences in IgG Fc Glycosylation Are Associated with Outcome of Pediatric Meningococcal Sepsis

mBio, 2018
Pediatric meningococcal sepsis often results in morbidity and/or death, especially in young children. Our understanding of the reasons why young children are more susceptible to both the meningococcal infection itself and a more fulminant course of the ...
Noortje de Haan, Navin P. Boeddha, Ebru Ekinci, Karli R. Reiding, Marieke Emonts, Jan A. Hazelzet, Manfred Wuhrer, Gertjan J. Driessen   +7 more
doaj   +1 more source

A Comprehensive Review of Meningococcal Disease Burden in India

Infectious Diseases and Therapy, 2020
Introduction Meningococcal disease caused by Neisseria meningitidis has a high case fatality rate. Of 12 distinct serogroups, A, B, C, W-135 (W) and Y cause the majority of infections.
Ashok Kumar Dutta, Subramanian Swaminathan, Veronique Abitbol, Shafi Kolhapure, Sripriya Sathyanarayanan   +4 more
doaj   +1 more source