Results 101 to 110 of about 143,652 (302)

Introduction and Rollout of a New Group A Meningococcal Conjugate Vaccine (PsA-TT) in African Meningitis Belt Countries, 2010–2014

Clinical Infectious Diseases, 2015
Background. A group A meningococcal conjugate vaccine (PsA-TT) was developed specifically for the African “meningitis belt” and was prequalified by the World Health Organization (WHO) in June 2010. The vaccine was first used widely in Burkina Faso, Mali,
M. Djingarey, Fabien V. K. Diomandé, R. Barry, D. Kandolo, F. Shirehwa, Clément Lingani, Ryan T Novak, C. Tévi-Bénissan, W. Perea, M. Preziosi, F. LaForce   +10 more
semanticscholar   +1 more source

Toll‐like receptor expression during inflammatory processes in human diseases

Rheumatology &Autoimmunity, Volume 5, Issue 1, Page 1-14, March 2025.
Chronic inflammation in different illnesses triggered by pathogen‐associated molecular patterns and damage associated molecular patterns recognized by Toll‐like receptors (TLRs). Abstract Multi‐cellular organisms, including humans, have evolved immune systems as defense mechanisms against pathogens. The immune system employs the Toll‐like receptor (TLR)
Prashant K. Dhakad, Raghav Mishra, Isha Mishra   +2 more
wiley   +1 more source

Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis

BMC Infectious Diseases, 2013
BackgroundBacterial meningitis is characterized by an intense inflammatory reaction contributing to neuronal damage. The aim of this study was to obtain a comparative analysis of cytokines and chemokines in patients with pneumococcal (PM) and ...
L. G. Coutinho, D. Grandgirard, S. Leib, L. F. Agnez-Lima   +3 more
semanticscholar   +1 more source

Time delays in the response to the Neisseria meningitidis serogroup C outbreak in Nigeria - 2017.

PLoS ONE, 2018
BackgroundNigeria reports high rates of mortality linked with recurring meningococcal meningitis outbreaks within the African meningitis belt. Few studies have thoroughly described the response to these outbreaks to provide strong and actionable public ...
Assad Hassan, G U Mustapha, Bola B Lawal, Aliyu M Na'uzo, Raji Ismail, Eteng Womi-Eteng Oboma, Oyeronke Oyebanji, Jeremiah Agenyi, Chima Thomas, Muhammad Shakir Balogun, Mahmood M Dalhat, Patrick Nguku, Chikwe Ihekweazu   +12 more
doaj   +1 more source

Vaccines against Meningococcal Diseases

Microorganisms, 2020
Neisseria meningitidis is the main cause of meningitis and sepsis, potentially life-threatening conditions. Thanks to advancements in vaccine development, vaccines are now available for five out of six meningococcal disease-causing serogroups (A, B, C, W,
Mariagrazia Pizza, Rafik Bekkat-Berkani, Rino Rappuoli   +2 more
doaj   +1 more source

A Case of Atypical Hemolytic Uremic Syndrome With a Complement Factor I Mutation Triggered by a Femoral Neck Fracture

Nephrology, Volume 30, Issue 3, March 2025.
ABSTRACT Atypical hemolytic uremic syndrome is a thrombotic microangiopathy caused by the abnormal activation of the alternative complement pathway. Mutations in complement‐related genes and autoantibodies against complement regulators are involved in the pathogenesis of this condition; the frequency of, and prognosis of patients harbouring, each ...
Toshiki Kano, Hiroaki Io, Yu Sasaki, Masahiro Muto, Sayaka Muto, Kei Ogiwara, Arisa Ikeda, Hiroyuki Iwasaki, Yusuke Suzuki   +8 more
wiley   +1 more source

Epidemiological changes in meningococcal meningitis in Niger from 2008 to 2011 and the impact of vaccination

BMC Infectious Diseases, 2013
BackgroundThe epidemiology of bacterial meningitis in the African ‘meningitis belt’ changes periodically. In order to design an effective vaccination strategy, we have examined the epidemiological and microbiological patterns of bacterial meningitis, and
J. Collard, B. Issaka, Maman Zaneidou, S. Hugonnet, P. Nicolas, M. Taha, B. Greenwood, J. Jusot   +7 more
semanticscholar   +1 more source

CLINICAL AND LIQUOR DIFFERENCES IN CASES OF SEROUS AND PURULENT MENINGITIS IN CHILDREN OF DIFFERENT AGE

Детские инфекции (Москва), 2015
The article presents features of clinical course and composition of cerebrospinal liquid in cases of purulent and serous meningitis depending on the age of the patients and the disease etiology.
E. M. Mazayeva, L. A. Alekseyeva, N. V. Skripchenko, T. V. Bessonova   +3 more
doaj   +1 more source

Clinical Presentations and Nosocomial Infections of Neurolisteriosis

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Neurolisteriosis is a listerial invasive disease, which is characterized by brain parenchymal and meningeal involvement, with a high fatality rate and frequent neurological sequelae. The main clinical presentations of neurolisteriosis are meningitis, meningoencephalitis, rhombencephalitis, and brain abscess.
Javier Vicente Trejos Pino, Juan Carlos Rodriguez Delgado, Satabdi Datta Choudhury   +2 more
wiley   +1 more source

Single Nucleotide Polymorphisms in Pathogen Recognition Receptor Genes Are Associated with Susceptibility to Meningococcal Meningitis in a Pediatric Cohort

PLoS ONE, 2013
Bacterial meningitis (BM) is a serious infection of the central nervous system, frequently occurring in childhood and often resulting in hearing loss, learning disabilities, and encephalopathy.
G. T. V. van Well, M. Sanders, S. Ouburg, Vinod Kumar, A. M. van Furth, S. Morré   +5 more
semanticscholar   +1 more source