Results 51 to 60 of about 71,819 (208)
Abstract Unnatural and unexplained deaths present critical challenges to the criminal justice, medico‐legal, and public health systems. This study explored forensic professionals' perspectives on the integration of point‐of‐care (POC) diagnostics into unnatural death investigations in South Africa.
Sebueng Ramatsokotla +8 more
wiley +1 more source
The introduction of a new Group A meningococcal conjugate vaccine, MenAfriVacR, has been a important public health success. Group A meningococcal meningitis has disappeared in all countries where the new Men A conjugate vaccine has been used at public ...
F. Marc LaForce +3 more
doaj +1 more source
Infection control in the brain and the eye
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Distinct Binding and Immunogenic Properties of the Gonococcal Homologue of Meningococcal Factor H Binding Protein [PDF]
10/03/14 MEB.
Tang Christoph M. +46 more
core +1 more source
ABSTRACT Clinically suspected invasive meningococcal disease can deteriorate rapidly in previously well children. Prompt recognition of the petechial–purpuric rash with shock, early empirical antibiotics, and aggressive supportive pediatric intensive care are cornerstones of management as multiorgan dysfunction and Acute Respiratory Distress Syndrome ...
Shatha Omar +6 more
wiley +1 more source
Meningococcal meningitis C in Tamil Nadu, public health perspectives
Meningococcal meningitis has rarely been reported in Tamil Nadu. We report here two children diagnosed with meningococcal meningitis in Vellore, Tamil Nadu, on May 2014. The causative strain was Neisseria meningitidis serotype C.
Kirubah Vasandhi David +2 more
doaj +1 more source
Meningitis Dipstick Rapid Test: Evaluating Diagnostic Performance During an Urban Neisseria Meningitidis Serogroup A Outbreak, Burkina Faso, 2007 [PDF]
Meningococcal meningitis outbreaks occur every year during the dry season in the "meningitis belt" of sub-Saharan Africa. Identification of the causative strain is crucial before launching mass vaccination campaigns, to assure use of the correct vaccine.
Dominique A. Caugant +31 more
core +1 more source
Complement Factor H‐Based Therapeutics: A Comprehensive Overview
Complement factor H is a central regulator of the complement system and thus a target for therapeutic intervention. In this review, we provide an overview of past and current factor H‐based therapeutic concepts and modalities to treat complement‐mediated diseases.
Sebastiaan M. W. R. Hamers +2 more
wiley +1 more source
ABSTRACT Introduction Clinical trials are evaluating the efficacy of serogroup B meningococcal (MenB) outer membrane vesicle (OMV) vaccines in preventing gonorrhoea. We assessed the global epidemiology of gonorrhoea and MenB invasive meningococcal disease (IMD) and reviewed national MenB‐OMV vaccination policies to inform potential use of these ...
Sami L. Gottlieb +9 more
wiley +1 more source
Risk and protective factors for meningococcal disease in adolescents: matched cohort study [PDF]
Objective: To examine biological and social risk factors for meningococcal disease in adolescents. Design: Prospective, population based, matched cohort study with controls matched for age and sex in 1:1 matching.
Stuart, J.M. +9 more
core

