Results 101 to 110 of about 590,194 (288)

Vaccination strategies and transmission of COVID-19: evidence across advanced countries [PDF]

arXiv, 2021
Given limited supply of approved vaccines and constrained medical resources, design of a vaccination strategy to control a pandemic is an economic problem. We use time-series and panel methods with real-world country-level data to estimate effects on COVID-19 cases and deaths of two key elements of mass vaccination - time between doses and vaccine type.
arxiv  

Meningococcal vaccine antigen diversity in global databases.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2015
The lack of an anti-capsular vaccine against serogroup B meningococcal disease has necessitated the exploration of alternative vaccine candidates, mostly proteins exhibiting varying degrees of antigenic variation. Analysis of variants of antigen-encoding
Carina Brehony, Dorothea M. C. Hill, J. Lucidarme, R. Borrow, M. Maiden   +4 more
semanticscholar   +1 more source

Toll‐like receptor expression during inflammatory processes in human diseases

Rheumatology &Autoimmunity, Volume 5, Issue 1, Page 1-14, March 2025.
Chronic inflammation in different illnesses triggered by pathogen‐associated molecular patterns and damage associated molecular patterns recognized by Toll‐like receptors (TLRs). Abstract Multi‐cellular organisms, including humans, have evolved immune systems as defense mechanisms against pathogens. The immune system employs the Toll‐like receptor (TLR)
Prashant K. Dhakad, Raghav Mishra, Isha Mishra   +2 more
wiley   +1 more source

An OMV Vaccine Derived from a Capsular Group B Meningococcus with Constitutive FetA Expression: Preclinical Evaluation of Immunogenicity and Toxicity. [PDF]

PLoS ONE, 2015
Following the introduction of effective protein-polysaccharide conjugate vaccines against capsular group C meningococcal disease in Europe, meningococci of capsular group B remain a major cause of death and can result in debilitating sequelae.
Gunnstein Norheim, Holly Sanders, Jardar W Mellesdal, Idunn Sundfør, Hannah Chan, Carina Brehony, Caroline Vipond, Chris Dold, Rory Care, Muhammad Saleem, Martin C J Maiden, Jeremy P Derrick, Ian Feavers, Andrew J Pollard   +13 more
doaj   +1 more source

A Multilingual Dataset of COVID-19 Vaccination Attitudes on Twitter [PDF]

arXiv, 2022
Vaccine hesitancy is considered as one main cause of the stagnant uptake ratio of COVID-19 vaccines in Europe and the US where vaccines are sufficiently supplied. Fast and accurate grasp of public attitudes toward vaccination is critical to address vaccine hesitancy, and social media platforms have proved to be an effective source of public opinions ...
arxiv  

The role of the gut microbiota in regulating responses to vaccination: current knowledge and future directions

The FEBS Journal, Volume 292, Issue 6, Page 1480-1499, March 2025.
Vaccination plays a crucial role in mediating protection against infectious diseases, but immune responses to vaccination are highly variable and frequently sub‐optimal in vulnerable populations. Here, we review the latest preclinical and clinical evidence demonstrating that the gut microbiota plays a significant role in regulating immune responses to ...
Charné Rossouw, Feargal J. Ryan, David J. Lynn   +2 more
wiley   +1 more source

Prediction by genetic MATS of 4CMenB vaccine strain coverage of invasive meningococcal serogroup B isolates circulating in Taiwan between 2003 and 2020

mSphere
Neisseria meningitidis serogroup B (NmB) strains have diverse antigens, necessitating methods for predicting meningococcal serogroup B (MenB) vaccine strain coverage. The genetic Meningococcal Antigen Typing System (gMATS), a correlate of MATS estimates,
Alessandro Muzzi, Min-Chi Lu, Elena Mori, Alessia Biolchi, Tiffany Fu, Laura Serino   +5 more
doaj   +1 more source

Safety and Immunogenicity of a Tetravalent Polysaccharide Vaccine Against Meningococcal Disease

Journal of the Formosan Medical Association, 2009
Meningococcal disease, including meningitis and sepsis, usually follows an invasive infection by Neisseria meningitidis, and is a major cause of death and morbidity worldwide.
Pei-Lan Shao, Luan-Yin Chang, Szu-Min Hsieh, Shan-Chwen Chang, Sung-Ching Pan, Chun-Yi Lu, Yu-Chia Hsieh, Chin-Yun Lee, Kurt Dobbelaere, Dominique Boutriau, Haiwen Tang, Hans L. Bock, Li-Min Huang   +12 more
doaj   +1 more source

Dynamic Vaccination Game in a Heterogeneous Mixing Population [PDF]

, 2019
Opposition to vaccination has long been a non-negligible public health phenomenon resulted from people's varied perceptions toward vaccination (e.g., vaccine-phobia). This paper investigates the voluntary vaccination behavior of a heterogeneous population during an epidemic outbreak, where each individual makes its own vaccination decision to minimize ...
arxiv   +1 more source

First Use of a Serogroup B Meningococcal Vaccine in the US in Response to a University Outbreak

Pediatrics, 2015
BACKGROUND: In 2013–2014, an outbreak of serogroup B meningococcal disease occurred among persons linked to a New Jersey university (University A). In the absence of a licensed serogroup B meningococcal (MenB) vaccine in the United States, the Food and ...
Lucy A. McNamara, Alice M. Shumate, Peter Johnsen, Jessica R Macneil, Manisha Patel, Tina Bhavsar, A. Cohn, Jill Dinitz-Sklar, Jonathan Duffy, Janet Finnie, Denise Garon, Robert Hary, Fang Hu, Hajime Kamiya, Hye-Joo Kim, John Kolligian, Janet Neglia, Judith E. Oakley, Jacqueline Wagner, Kathy Wagner, Xin Wang, Yon C. Yu, Barbara Montana, Christina Tan, Robin Izzo, Thomas A. Clark   +25 more
semanticscholar   +1 more source