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Meningococcal Vaccines: Current Status and Emerging Strategies
Vaccines, 2018 Neisseria meningitidis causes most cases of bacterial meningitis. Meningococcal meningitis is a public health burden to both developed and developing countries throughout the world.
Pumtiwitt C. McCarthy +2 more
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Current status and challenges of meningococcal vaccines development in China
Zhongguo gonggong weisheng, 2022 Vaccination is the most effective and economical way to prevent meningococcal meningitis. In the past few decades, with widespread use of meningococcal vaccines, the incidence of meningococcal meningitis has dropped significantly. There are some vaccines
Ying-hua XU, Ya-nan LI, Qiang YE
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World Experience in the Use Serogroup B Meningococcal Vaccines (literature review)
Эпидемиология и вакцинопрофилактика, 2022 Relevance. The success of vaccine prophylaxis of meningococcal infection depends on the composition and properties of vaccine preparations and the strict implementation of recommendations on vaccine prophylaxis tactics by the territorial epidemiological ...
I. S. Koroleva, M. A. Koroleva
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Meningococcal Vaccinations [PDF]
Infectious Diseases and Therapy, 2016 Neisseria meningitidis, a gram-negative diplococcal bacterium, is a common asymptomatic nasopharyngeal colonizer that may infrequently lead to invasive disease in the form of meningitis or bacteremia. Six serogroups (A, B, C, W, X and Y) are responsible for the majority of invasive infections.
Crum-Cianflone, Nancy, Sullivan, Eva
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Pediatric Infectious Disease Journal, 2004 The 5 major pathogenic serogroups of the Gram-negative encapsulated bacterium Neisseria meningitidis are A, B, C, Y, and W135. In the 1960s, vaccines consisting of purified capsular polysaccharide antigens were developed against serogroups A, C, Y, and W135.
Rüggeberg, J, Pollard, A
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Promising pharmaceutical development of vaccines for the prevention of meningococcal infection
Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Meningococcal infection (MI) refers to anthroponoses; is an acute infectious disease with an aerosol transmission mechanism, characterized by various forms of the infectious process: from local (nasopharyngitis) and asymptomatic infections to generalized
Maria V. Savkina +3 more
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Human Vaccines & Immunotherapeutics, 2012 Meningococcal meningitis is caused by Neisseria meningitidis, a gram-negative, aerobic, encapsulated diplococcus. Meningococci are divided into numerous serogroups based on the composition of their capsular polysaccharide (Ps) antigens. At least 13 serogroups have been described: A, B, C, D, 29E, H, I, K, L, W-135, X, Y and Z.
Ramesh, Verma, Pardeep, Khanna
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mSphere, 2018 Neisseria meningitidis is a common cause of bacterial meningitis in children and young adults worldwide. The 4CMenB vaccine (Bexsero), developed to combat meningococcal serogroup B (MenB) disease, contains subcapsular antigens that may induce immunity ...
Robert M. Mulhall +12 more
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Human Vaccines & Immunotherapeutics, 2022 Vaccination offers the best way to prevent invasive meningococcal disease (IMD). As demonstrated in countries with national immunization programs (NIPs) against IMD, meningococcal conjugate vaccines have contributed to significant declines in incidence ...
Gary S. Marshall +3 more
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Infectious Diseases and Therapy, 2019 Neisseria meningitidis is a major cause of meningitis and septicemia with cases, outbreaks, and epidemics reported globally in industrialized and non-industrialized countries. N. meningitidis is categorized into 12 serogroups; however, only 5 serogroups (
Jessica Presa +4 more
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