Results 51 to 60 of about 13,322 (172)

Complement Factor H‐Based Therapeutics: A Comprehensive Overview

European Journal of Immunology, Volume 56, Issue 7, July 2026.
Complement factor H is a central regulator of the complement system and thus a target for therapeutic intervention. In this review, we provide an overview of past and current factor H‐based therapeutic concepts and modalities to treat complement‐mediated diseases.
Sebastiaan M. W. R. Hamers, Emmy J. Buter, Richard B. Pouw   +2 more
wiley   +1 more source

Las vacunas conjugadas contra la enfermedad meningococica causadas por los serogrupos A, C, W-135, Y

VacciMonitor, 2009
Review the current evidence on available and candidate quadrivalent meningococcal conjugate vaccines. Methods: A comprehensive overview of data on the currently available A-C-W135-Y meningococcal vaccine and the results of late stage development of novel
Marcos Aurelio P. Sáfadi
doaj  

Defining the Efficacy of Meningococcal B Vaccines Against Gonococcal Acquisition: The Current Landscape

Journal of the International AIDS Society, Volume 29, Issue S2, July 2026.
ABSTRACT Introduction Gonorrhoea is a major global sexually transmitted infection, with rising incidence and increasing antimicrobial resistance threatening current control strategies. If untreated, Neisseria gonorrhoeae can lead to severe reproductive health sequelae. Gonorrhoea is also linked to increased HIV acquisition and transmission.
Kate L. Seib, Andrew E. Grulich
wiley   +1 more source

Potential Use of Neisseria meningitidis Serogroup B Vaccines to Prevent Neisseria gonorrhoeae Infection: Epidemiological Considerations

Journal of the International AIDS Society, Volume 29, Issue S2, July 2026.
ABSTRACT Introduction Clinical trials are evaluating the efficacy of serogroup B meningococcal (MenB) outer membrane vesicle (OMV) vaccines in preventing gonorrhoea. We assessed the global epidemiology of gonorrhoea and MenB invasive meningococcal disease (IMD) and reviewed national MenB‐OMV vaccination policies to inform potential use of these ...
Sami L. Gottlieb, Jane Rowley, Nuria Balibrea, Dominique A. Caugant, Ray Borrow, Antoine Durupt, Helen S. Marshall, Maeve B. Mello, Marco Aurelio Sáfadi, Marie‐Pierre Preziosi   +9 more
wiley   +1 more source

Meningococcal disease: changes in epidemiology and prevention

Clinical Epidemiology, 2012
Qiuzhi Chang,1 Yih-Ling Tzeng,2 David S Stephens1–31Department of Epidemiology, Rollins School of Public Health, Emory University, 2Department of Medicine, Emory University School of Medicine, 3Laboratories of Microbial Pathogenesis, Department
Chang Q, Tzeng YL, Stephens DS
doaj  

Overwhelming Post‐Splenectomy Sepsis From Capnocytophaga canimorsus

International Journal of Laboratory Hematology, EarlyView.
Maitlyn Hsia, Maud Ahmad, Cyrus C. Hsia, Benjamin Chin‐Yee   +3 more
wiley   +1 more source

Immune Dysregulation in Branched Chain Organic Acidemias

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Organic acidemias (OAs) are a group of inherited disorders, most commonly caused by defects in mitochondrial enzymes involved in amino acid and fatty acid metabolism. While they characteristically present with metabolic and neurological crises, growing evidence reveals a significant burden of chronic immune dysregulation in some disorders and ...
Abdul L. Shakerdi, Jack Drda, Justin A. Dutta, Jerry Vockley   +3 more
wiley   +1 more source

Adaptive Sequential Multiple Hypotheses Testing for Concomitant Vaccine Safety Surveillance

Statistics in Medicine, Volume 45, Issue 15-17, July 2026.
ABSTRACT When multiple vaccines are simultaneously recommended, a statistical method to monitor adverse events accounting for multiple combinations of vaccine exposure rather than each vaccine individually is preferred. We introduce an adaptive multiple hypotheses test method for rapidly detecting increased risks of adverse events from one or more ...
Ivair R. Silva, Lily Wang, Judith C. Maro   +2 more
wiley   +1 more source

EPIDEMIOLOGY AND PREVENTION OF MENINGOCOCCAL DISEASE: A CRITICAL APPRAISAL OF VACCINE POLICIES

Педиатрическая фармакология, 2012
Meningococcal disease is characterized by a marked variation in incidence and serogroup distribution by region and over time. In several European countries, Canada and Australia, immunization programs, including universal vaccination of infants or ...
Marco AP Safadi, E David G Mcintosh
doaj   +1 more source

Prevention of Meningococcal Disease: Knowledge, Attitudes, and Practices of General Practitioners and Primary Care Pediatricians in South Italy

Vaccines
Background: The purpose of this study was to evaluate the knowledge, attitude, and current practices about prevention of meningococcal disease among general practitioners (GPs) and primary care pediatricians (PCPs) in Italy.
Silvia Angelillo, Concetta Paola Pelullo, Francesca Licata, Raffaele Lanzano, Francesco Napolitano, Gabriella Di Giuseppe   +5 more
doaj   +1 more source