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THE POISON OF THE MENINGOCOCCUS. [PDF]
Perhaps it would be less presumptuous to entitle this communication "A Poison from the Meningococcus." By this expedient one might at least evade some of the perplexities which now surround the problems relating to the composition, varieties and effects of toxic substances elaborated by pathogenic bacteria.
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During 2010, outbreaks of serogroup C meningococcal (MenC) disease occurred in 2 oil refineries in São Paulo State, Brazil, leading to mass vaccination of employees at 1 refinery with a meningococcal polysaccharide A/C vaccine.
Marco Aurelio Palazzi Sáfadi +13 more
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The endotoxin of the meningococcus [PDF]
1. The view is advanced that the endotoxin of the meningococcus is one of a group of thermostable intracellular bacterial poisons, and that it is not a specific antigenic toxin. 2. The inability of the “endotoxin” to function as an antigen does not lessen its importance as a pathogenic factor in cerebrospinal fever, since the lesions that are ...
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Gay, F. P., Minaker, A. J.
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Sialic acid mediated mechanical activation of β2 adrenergic receptors by bacterial pili
Meningococcus utilizes β-arrestin selective activation of endothelial cell β2 adrenergic receptor (β2AR) to cause meningitis in humans. Here authors report that Meningococcus triggers β2AR signaling by exerting forces on β2AR glycans that terminally ...
Zoe Virion +11 more
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An Anomalous Meningococcus [PDF]
(1) An unusual strain of meningococcus has been isolated which produces minute “dew drop” colonies. This character has persisted throughout a large number of successive generations. Every culture, however, has shown lateral off-shoots consisting of colonies which have the size and appearance of those of typical meningococci.
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Protein conjugate polysaccharide vaccines: Challenges in development and global implementation
Pneumonia and meningitis caused by Haemophilus influenzae type b, Streptococcus pneumoniae, and Neisseria meningitidis are among the leading causes of under five mortality and morbidity.
Manisha Nair
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Rise in Group W Meningococcal Carriage in University Students, United Kingdom
MenACWY conjugate vaccination was recently introduced in the United Kingdom for adolescents and young adults to reduce disease from infection by Neisseria meningitidis group W.
Neil J. Oldfield +11 more
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Conquering the Meningococcus [PDF]
Since the first outbreaks of meningococcal meningitis were first described in Geneva in 1804 and in New England in 1806, and since the discovery of the causative agent by Weichselbaum in 1887 and the beginning of epidemics of meningococcal meningitis in the sub-Saharan Africa approximately 100 years ago, Neisseria meningitidis has been recognized as ...
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